In animals, the double-stranded RNA-specific endonuclease Dicer produces two classes of
functionally distinct, tiny RNAs: microRNAs (miRNAs) and small interfering RNAs (siRNAs) …

RNAi is a gene-silencing phenomenon triggered by double-stranded (ds) RNA and involves
the generation of 21 to 26 nt RNA segments that guide mRNA destruction. In Caenorhabditis …

Micro RNAs are a large family of noncoding RNAs of 21–22 nucleotides whose functions are
generally unknown. Here a large subset of Drosophila micro RNAs is shown to be perfectly …

Abstract Background The microRNAs (miRNAs) are an extensive class of small noncoding
RNAs (18 to 25 nucleotides) with probable roles in the regulation of gene expression. In …

Non-coding RNA (ncRNA) genes produce functional RNA molecules rather than encoding
proteins. However, almost all means of gene identification assume that genes encode …

MicroRNAs (miRNAs) are a class of noncoding RNAs found in organisms as evolutionarily
distant as plants and mammals, yet most of the mRNAs they regulate are unknown. Here we …

Micro-RNAs (miRNAs) are regulatory molecules that mediate effects by interacting with
messenger RNA (mRNA) targets. Here we show that Arabidopsis thaliana miRNA 39 (also …

We propose that the microRNA milieu, unique to each cell type, productively dampens the
expression of thousands of mRNAs and provides important context for the evolution of all …

MicroRNAs (miRNAs) are genomically encoded small RNAs used by organisms to regulate
the expression of proteins generated from messenger RNA transcripts. The in vivo …

MicroRNAs (miRNAs) play critical roles in development, and dysregulation of miRNA
expression has been observed in human malignancies. Recent evidence suggests that the …