The role of bacteria in the caries process: ecological perspectives

N Takahashi, B Nyvad - Journal of dental research, 2011 - journals.sagepub.com
Dental biofilms produce acids from carbohydrates that result in caries. According to the
extended caries ecological hypothesis, the caries process consists of 3 reversible stages …

Saliva as the sole nutritional source in the development of multispecies communities in dental plaque

NS Jakubovics - Microbiology spectrum, 2015 - Am Soc Microbiol
Dental plaque is a polymicrobial biofilm that forms on the surfaces of teeth and, if
inadequately controlled, can lead to dental caries or periodontitis. Nutrient availability is the …

Deglycosylation of human glycoconjugates by the sequential activities of exoglycosidases expressed by Streptococcus pneumoniae

SJ King, KR Hippe, JN Weiser - Molecular microbiology, 2006 - Wiley Online Library
Streptococcus pneumoniae produces three surface‐associated exoglycosidases; a
neuraminidase, NanA, a β‐galactosidase, BgaA, and a β‐N‐acetylglucosaminidase, StrH …

Growth of Streptococcus pneumoniae on Human Glycoconjugates Is Dependent upon the Sequential Activity of Bacterial Exoglycosidases

AM Burnaugh, LJ Frantz, SJ King - Journal of bacteriology, 2008 - Am Soc Microbiol
In the human host, Streptococcus pneumoniae encounters a variety of glycoconjugates,
including mucin, host defense molecules, and glycans associated with the epithelial surface …

Biofilm Mode of Growth of Streptococcus intermedius Favored by a Competence-Stimulating Signaling Peptide

FC Petersen, D Pecharki, AA Scheie - Journal of bacteriology, 2004 - Am Soc Microbiol
Gram-positive and gram-negative bacteria use quorum sensing to coordinate population
behavior. In several streptococci, quorum sensing mediated by competence-stimulating …

Host Glycan Sugar-Specific Pathways in Streptococcus pneumonia: Galactose as a Key Sugar in Colonisation and Infection

L Paixão, J Oliveira, A Veríssimo, S Vinga… - PloS one, 2015 - journals.plos.org
The human pathogen Streptococcus pneumoniae is a strictly fermentative organism that
relies on glycolytic metabolism to obtain energy. In the human nasopharynx S. pneumoniae …

The effects of hormones and vaginal microflora on the glycome of the female genital tract: cervical-vaginal fluid

BJ Moncla, CA Chappell, BM Debo, LA Meyn - PloS one, 2016 - journals.plos.org
In this study, we characterized the glycome of cervical-vaginal fluid, collected with a
Catamenial cup. We quantified: glycosidase levels; sialic acid and high mannose specific …

Analysis of a new family of widely distributed metal-independent α-mannosidases provides unique insight into the processing of N-linked glycans

KJ Gregg, WF Zandberg, JH Hehemann… - Journal of Biological …, 2011 - ASBMB
The modification of N-glycans by α-mannosidases is a process that is relevant to a large
number of biologically important processes, including infection by microbial pathogens and …

Intervening in symbiotic cross-kingdom biofilm interactions: a binding mechanism-based nonmicrobicidal approach

HE Kim, A Dhall, Y Liu, M Bawazir, H Koo, G Hwang - MBio, 2021 - Am Soc Microbiol
Early childhood caries is a severe oral disease that results in aggressive tooth decay.
Particularly, a synergistic association between a fungus, Candida albicans, and a cariogenic …

Salivary gel‐forming mucin MUC5B–a nutrient for dental plaque bacteria

C Wickström, G Svensäter - Oral microbiology and immunology, 2008 - Wiley Online Library
Introduction: Model systems with oral bacteria from dental plaque have demonstrated that
the utilization of complex glycoproteins as a food source cannot be undertaken by single …