PDMS microfluidics: A mini review

K Raj M, S Chakraborty - Journal of Applied Polymer Science, 2020 - Wiley Online Library
Polydimethylsiloxane (PDMS) is hailed as one of the foundational materials for microfluidics.
Though a silicone‐based elastomer of many desirable properties, the emergence of …

C. elegans in high-throughput drug discovery

LP O'Reilly, CJ Luke, DH Perlmutter… - Advanced drug delivery …, 2014 - Elsevier
Caenorhabditis elegans has been proven to be a useful model organism for investigating
molecular and cellular aspects of numerous human diseases. More recently, investigators …

Rotational manipulation of single cells and organisms using acoustic waves

D Ahmed, A Ozcelik, N Bojanala, N Nama… - Nature …, 2016 - nature.com
The precise rotational manipulation of single cells or organisms is invaluable to many
applications in biology, chemistry, physics and medicine. In this article, we describe an …

Droplet microfluidics: recent developments and future applications

XC i Solvas, A DeMello - Chemical Communications, 2011 - pubs.rsc.org
We report recent advances in the field of droplet-based microfluidics. Specifically, we
highlight the unique features of such platforms for high-throughput experimentation; …

High-content behavioral analysis of Caenorhabditis elegans in precise spatiotemporal chemical environments

DR Albrecht, CI Bargmann - Nature methods, 2011 - nature.com
To quantitatively understand chemosensory behaviors, it is desirable to present many
animals with repeatable, well-defined chemical stimuli. To that end, we describe a …

Large-scale microfluidics providing high-resolution and high-throughput screening of Caenorhabditis elegans poly-glutamine aggregation model

S Mondal, E Hegarty, C Martin, SK Gökce… - Nature …, 2016 - nature.com
Next generation drug screening could benefit greatly from in vivo studies, using small animal
models such as Caenorhabditis elegans for hit identification and lead optimization. Current …

Surface acoustic waves enable rotational manipulation of Caenorhabditis elegans

J Zhang, S Yang, C Chen, JH Hartman, PH Huang… - Lab on a Chip, 2019 - pubs.rsc.org
Controllable, precise, and stable rotational manipulation of model organisms is valuable in
many biomedical, bioengineering, and biophysics applications. We present an …

Soil-on-a-Chip: microfluidic platforms for environmental organismal studies

CE Stanley, G Grossmann, XC i Solvas, AJ deMello - Lab on a Chip, 2016 - pubs.rsc.org
Soil is the habitat of countless organisms and encompasses an enormous variety of dynamic
environmental conditions. While it is evident that a thorough understanding of how …

3D acoustic manipulation of living cells and organisms based on 2D array

Y Yang, T Ma, Q Zhang, J Huang, Q Hu… - IEEE Transactions …, 2022 - ieeexplore.ieee.org
Flexible manipulation techniques for living cells and organisms are extremely useful tools for
fundamental biomedical and life science research. Acoustic tweezers, which permit non …

[HTML][HTML] Microfluidics as a tool for C. elegans research

A San-Miguel, H Lu - WormBook: The Online Review of C. elegans …, 2018 - ncbi.nlm.nih.gov
Microfluidics has emerged as a set of powerful tools that have greatly advanced some areas
of biological research, including research using C. elegans. The use of microfluidics has …