[HTML][HTML] Dysregulation of metabolic pathways in pulmonary fibrosis
R Rajesh, R Atallah, T Bärnthaler - Pharmacology & Therapeutics, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disorder of unknown origin and
the most common interstitial lung disease. It progresses with the recruitment of fibroblasts …
the most common interstitial lung disease. It progresses with the recruitment of fibroblasts …
[HTML][HTML] Comprehensive review of potential drugs with anti-pulmonary fibrosis properties
J Ma, G Li, H Wang, C Mo - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Pulmonary fibrosis is a chronic and progressive lung disease characterized by the
accumulation of scar tissue in the lungs, which leads to impaired lung function and reduced …
accumulation of scar tissue in the lungs, which leads to impaired lung function and reduced …
Multiomics analysis reveals the mechanical stress-dependent changes in trabecular meshwork cytoskeletal-extracellular matrix interactions
A Soundararajan, T Wang, R Sundararajan… - Frontiers in cell and …, 2022 - frontiersin.org
Trabecular meshwork (TM) tissue is subjected to constant mechanical stress due to the
ocular pulse created by the cardiac cycle. This brings about alterations in the membrane …
ocular pulse created by the cardiac cycle. This brings about alterations in the membrane …
Re-Examining the Role of Pulmonary Lipids in the Pathogenesis of Pulmonary Fibrosis
M O'Callaghan, EJ Tarling, JP Bridges… - American Journal of …, 2024 - atsjournals.org
Pulmonary fibrosis (PF) can be idiopathic or driven by a specific insult or disease process.
Inflammation plays a role in the pathophysiology, the extent of which remains a longstanding …
Inflammation plays a role in the pathophysiology, the extent of which remains a longstanding …
Fatty acids metabolism in ozone-induced pulmonary inflammatory injury: Evidence, mechanism and prevention
M Li, X Kong, X Jian, Y Bo, X Miao, H Chen… - Science of The Total …, 2024 - Elsevier
Ozone (O 3) is a major air pollutant that directly threatens the respiratory system, lung fatty
acid metabolism disorder is an important molecular event in pulmonary inflammatory …
acid metabolism disorder is an important molecular event in pulmonary inflammatory …
Downregulation of HMGCS2 mediated AECIIs lipid metabolic alteration promotes pulmonary fibrosis by activating fibroblasts
J Yang, X Pan, M Xu, Y Li, C Liang, L Liu, Z Li… - Respiratory …, 2024 - Springer
Background Abnormal lipid metabolism has recently been reported as a crucial signature of
idiopathic pulmonary fibrosis (IPF). However, the origin and biological function of the lipid …
idiopathic pulmonary fibrosis (IPF). However, the origin and biological function of the lipid …
Effects of Anti-Fibrotic Drugs on Transcriptome of Peripheral Blood Mononuclear Cells in Idiopathic Pulmonary Fibrosis
D Ishii, T Kawasaki, H Sato, K Tatsumi… - International Journal of …, 2024 - mdpi.com
Two anti-fibrotic drugs, pirfenidone (PFD) and nintedanib (NTD), are currently used to treat
idiopathic pulmonary fibrosis (IPF). Peripheral blood mononuclear cells (PBMCs) are …
idiopathic pulmonary fibrosis (IPF). Peripheral blood mononuclear cells (PBMCs) are …
Ferroptosis in organ fibrosis: From mechanisms to therapeutic medicines
W Lai, B Wang, R Huang, C Zhang, P Fu… - Journal of Translational …, 2024 - degruyter.com
Fibrosis occurs in many organs, and its sustained progress can lead to organ destruction
and malfunction. Although numerous studies on organ fibrosis have been carried out, its …
and malfunction. Although numerous studies on organ fibrosis have been carried out, its …
Beyond the Acute Phase: Long-Term Impact of COVID-19 on Functional Capacity and Prothrombotic Risk—A Pilot Study
Background and Objectives: Assessment of the prothrombotic, proinflammatory, and
functional status of a cohort of COVID-19 patients at least two years after the acute infection …
functional status of a cohort of COVID-19 patients at least two years after the acute infection …
MOTS-c: A potential anti-pulmonary fibrosis factor derived by mitochondria
Z Zhang, D Chen, K Du, Y Huang, X Li, Q Li, X Lv - Mitochondrion, 2023 - Elsevier
Pulmonary fibrosis (PF) is a serious lung disease characterized by diffuse alveolitis and
disruption of alveolar structure, with a poor prognosis and unclear etiopathogenesis. While …
disruption of alveolar structure, with a poor prognosis and unclear etiopathogenesis. While …