Cancer, ranked as the second leading cause of mortality worldwide, leads to the death of
approximately seven million people annually, establishing itself as one of the most …

Introduction: The incorporation of immune checkpoint inhibitors in the oncologists' arsenal is
a milestone in cancer therapeutics, though not being devoid of toxicities. Areas covered: The …

Oncolytic viruses (OVs) promote the anti-tumor immune response as their replication, and
the subsequent lysis of tumor cells, triggers the activation of immune-sensing pathways …

检查点抑制剂 (immune checkpoint inhibitors, ICIs) 治疗是目前最常用的免疫治疗方案,
已被批准用于黑色素瘤, 肾癌, 头颈癌, 膀胱癌等多种肿瘤的临床治疗, 在肺癌治疗中更是取得 …

Currently, gastric cancer is the third most common cause of cancer‑associated mortality
worldwide. Oncolytic virotherapy using herpes simplex virus (HSV) has emerged as a novel …

Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer
treatment, offering a unique potential to selectively target malignant cells while sparing …

Background: Head and neck squamous cell carcinoma (HNSC) is a prevalent and
heterogeneous malignancy with poor prognosis and high mortality rates. There is significant …

Using immunotherapy to treat cancers can be traced back to the 1890s, where a New York
physician William Coley used heat-killed bacteria to treat cancer patients, which became …

Gliomas are highly aggressive intracranial tumors that are difficult to resect and have high
lethality and recurrence rates. According to WHO grading criteria, glioblastoma with wild …

检查点抑制剂（ immune checkpoint inhibitors, ICIs） 治疗是目前最常用的免疫治疗方案，
已被批准用于黑色素瘤、 肾癌、 头颈癌、 膀胱癌等多种肿瘤的临床治疗， 在肺癌治疗中更是取得 …