Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Targeted cancer immunotherapy: nanoformulation engineering and clinical translation

M Yu, W Yang, W Yue, Y Chen - Advanced Science, 2022 - Wiley Online Library
With the rapid growth of advanced nanoengineering strategies, there are great implications
for therapeutic immunostimulators formulated in nanomaterials to combat cancer. It is crucial …

Ferroptosis and its potential role in glioma: from molecular mechanisms to therapeutic opportunities

Y Luo, G Tian, X Fang, S Bai, G Yuan, Y Pan - Antioxidants, 2022 - mdpi.com
Glioma is the most common intracranial malignant tumor, and the current main standard
treatment option is a combination of tumor surgical resection, chemotherapy and …

Enhanced therapeutic effect of optimized melittin-dKLA, a peptide agent targeting M2-like tumor-associated macrophages in triple-negative breast cancer

S Kim, I Choi, IH Han, H Bae - International Journal of Molecular Sciences, 2022 - mdpi.com
Triple-negative breast cancer (TNBC) is characterized by a high possibility of metastasis. M2-
like tumor-associated macrophages (TAMs) are the main components of the tumor …

Targeting the innate immune system with nanoparticles for cancer immunotherapy

K Li, Z Zhang, Y Mei, M Li, Q Yang, Q Wu… - Journal of Materials …, 2022 - pubs.rsc.org
Various cancer therapies have advanced remarkably over the past decade. Unlike the direct
therapeutic targeting of tumor cells, cancer immunotherapy is a new strategy that boosts the …

Calcium-deprivation-activated immune responses for solid tumor regression

Q Bao, H Fu, Y Guo, P Hu, J Shi - Chem, 2024 - cell.com
Cancer immunotherapy is currently one of the most attractive therapeutics against
hematological malignancies, but unfortunately, the outcomes remain unsatisfactory in most …

Prognostic value of p16, p53, and pcna in sarcoma and an evaluation of immune infiltration

D Cai, X Ma, H Guo, H Zhang, A Bian, H Yu… - Journal of Orthopaedic …, 2022 - Springer
Abstract Background p16, p53, and proliferating cell nuclear antigen (pcna) genes play
significant roles in many chromatin modifications and have been found to be highly …

Harnessing biomaterial architecture to drive anticancer innate immunity

MA Davis, E Cho, MH Teplensky - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Immunomodulation is a powerful therapeutic approach that harnesses the body's own
immune system and reprograms it to treat diseases, such as cancer. Innate immunity is key …

[HTML][HTML] Nanomedicine approaches for treatment of hematologic and oncologic malignancies

P Nteli, DE Bajwa, D Politakis… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Cancer is a leading cause of death worldwide. Nowadays, the therapies are inadequate and
spur demand for improved technologies. Rapid growth in nanotechnology and novel …

Probiotic-derived silver nanoparticles target mTOR/MMP-9/BCL-2/dependent AMPK activation for hepatic cancer treatment

A Elmetwalli, MO Abdel-Monem, AH El-Far, GS Ghaith… - Medical Oncology, 2024 - Springer
Recent advances in nanotechnology have offered novel ways to combat cancer. By utilizing
the reducing capabilities of Lactobacillus acidophilus, silver nanoparticles (AgNPs) are …