The role of testosterone in the elderly: what do we know?

B Barone, L Napolitano, M Abate, L Cirillo… - International journal of …, 2022 - mdpi.com
Testosterone is the most important hormone in male health. Aging is characterized by
testosterone deficiency due to decreasing testosterone levels associated with low testicular …

[HTML][HTML] Sex and gender differences in Alzheimer's disease: genetic, hormonal, and inflammation impacts

Z Kolahchi, N Henkel, MA Eladawi… - International Journal of …, 2024 - mdpi.com
Two-thirds of Americans with Alzheimer's disease are women, indicating a profound
variance between the sexes. Variances exist between the sexes in the age and intensity of …

Moschus ameliorates glutamate-induced cellular damage by regulating autophagy and apoptosis pathway

D Xie, C Song, T Qin, Z Zhai, J Cai, J Dai, T Sun… - Scientific Reports, 2023 - nature.com
Abstract Alzheimer's disease (AD), a neurodegenerative disorder, causes short-term
memory and cognition declines. It is estimated that one in three elderly people die from AD …

Early Detection of Alzheimer's Disease in Postmenopausal Women Using Thalamic Subnuclear Volumetry

GW Kim, K Park, GW Jeong - Journal of Clinical Medicine, 2023 - mdpi.com
Alzheimer's disease (AD) and aging are intrinsically interconnected with each other and are
mediated by molecular, cellular, and biological systems. In particular, a specific pattern of …

Carbon-chain length determines the binding affinity and inhibitory strength of per-and polyfluoroalkyl substances on human and rat steroid 5α-reductase 1 activity

R Cui, L Ye, X Qiao, S Wang, K Zheng, J Yang… - Chemico-Biological …, 2024 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are widely used synthetic chemicals that persist
in the environment and bioaccumulate in animals and humans. There is growing evidence …

Surgical tolerability and frailty in elderly patients undergoing robot-assisted radical prostatectomy: A narrative review

Y Yamada, S Taguchi, H Kume - Cancers, 2022 - mdpi.com
Simple Summary Life expectancy in Western countries and East Asian countries has
incremented over the past decades, resulting in a rapidly aging world, while in general …

Is there a connection between the metabolism of copper, sulfur, and molybdenum in Alzheimer's disease? New insights on disease etiology

FC Coelho, G Cerchiaro, SES Araújo… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) and other forms of dementia was ranked 3rd in both the Americas
and Europe in 2019 in a World Health Organization (WHO) publication listing the leading …

Stress-related cellular pathophysiology as a crosstalk risk factor for neurocognitive and psychiatric disorders

IS Palamarchuk, GM Slavich, T Vaillancourt, TK Rajji - BMC neuroscience, 2023 - Springer
In this narrative review, we examine biological processes linking psychological stress and
cognition, with a focus on how psychological stress can activate multiple neurobiological …

Among men, androgens are associated with a decrease in Alzheimer's disease risk

CDJ Kusters, KC Paul, T Romero… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Increased levels of sex hormones have been hypothesized to decrease
Alzheimer's disease (AD) risk. We assessed the association between sex steroid hormones …

Testosterone and aging male, a perspective from a developing country

B Nguyen Hoai, L Hoang, T Nguyen Cao… - The Aging …, 2023 - Taylor & Francis
Purpose Hypogonadism is associated with a wide range of physical and psychological
symptoms that can affect the overall health of men. However, in a developing country, there …