Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …

Heparan sulfate proteoglycans (HSPG) are composed of unbranched, negatively charged
heparan sulfate (HS) polysaccharides attached to a variety of cell surface or extracellular …

Viruses are a constant threat to global health as highlighted by the current COVID-19
pandemic. Currently, lack of data underlying how the human host interacts with viruses …

Throughout the last decade, chikungunya virus (CHIKV) and Zika virus (ZIKV) infections
have spread globally, causing a spectrum of disease that ranges from self-limited febrile …

3-3 protein family members facilitate the translocation of RIG-I-like receptors (RLRs) to
organelles that mediate downstream RLR signaling, leading to interferon production. 14-3 …

Oxidative stress is induced once the balance of generation and neutralization of reactive
oxygen species (ROS) is broken in the cell, and it plays crucial roles in a variety of natural …

Transmission from an infected mosquito to a host is an essential process in the life cycle of
mosquito-borne flaviviruses. Numerous studies have demonstrated that mosquito saliva …

Recent decades have witnessed the emergence and re-emergence of numerous medically
important viruses that cause central nervous system (CNS) infections in children, eg, Zika …

The re-emergence of Zika virus (ZIKV) in the Western Hemisphere has resulted in global
public health crisis since 2015. ZIKV preferentially infects and targets human neural …

Glycans are among the most important cell molecular components. However, given their
structural diversity, their functions have not been fully explored. Glycosylation is a vital post …