Understanding Clostridium difficile colonization

MJT Crobach, JJ Vernon, VG Loo… - Clinical microbiology …, 2018 - Am Soc Microbiol
Clostridium difficile is the main causative agent of antibiotic-associated and health care-
associated infective diarrhea. Recently, there has been growing interest in alternative …

[HTML][HTML] Asymptomatic Clostridium difficile colonization: epidemiology and clinical implications

L Furuya-Kanamori, J Marquess, L Yakob… - BMC infectious …, 2015 - Springer
Abstract Background The epidemiology of Clostridium difficile infection (CDI) has changed
over the past decades with the emergence of highly virulent strains. The role of …

Colonization with toxinogenic C. difficile upon hospital admission, and risk of infection: a systematic review and meta-analysis

IM Zacharioudakis, FN Zervou, EE Pliakos… - Official journal of the …, 2015 - journals.lww.com
Objectives: It has been suggested that colonization withC. difficileprotects from infection.
Nevertheless, the association between carriage of toxinogenic strains and ensuingC …

Clostridium difficile infection following systemic antibiotic administration in randomised controlled trials: a systematic review and meta-analysis

KZ Vardakas, KK Trigkidis, E Boukouvala… - International journal of …, 2016 - Elsevier
Antibiotics have been the most important risk factor for Clostridium difficile infection (CDI).
However, only data from non-randomised studies have been reviewed. We sought to …

[HTML][HTML] The emergence of Clostridium difficile infection in Asia: A systematic review and meta-analysis of incidence and impact

NZ Borren, S Ghadermarzi, S Hutfless… - PloS one, 2017 - journals.plos.org
Background Clostridium difficile infection (CDI) is the most common healthcare associated
infection and is highly prevalent in Europe and North America. Limited data is available on …

Colonization versus carriage of Clostridium difficile

CJ Donskey, S Kundrapu… - Infectious Disease Clinics, 2015 - id.theclinics.com
Many people acquiring colonization with toxigenic strains of Clostridium difficile become
asymptomatic carriers. 1–6 In addition, many patients with C difficile infection (CDI) become …

[HTML][HTML] Asymptomatic Carriers of Toxigenic C. difficile in Long-Term Care Facilities: A Meta-Analysis of Prevalence and Risk Factors

PD Ziakas, IM Zacharioudakis, FN Zervou, C Grigoras… - PloS one, 2015 - journals.plos.org
Background The impact of Clostridium difficile colonization in C. difficile infection (CDI) is
inadequately explored. As a result, asymptomatic carriage is not considered in the …

Detection of Clostridium difficile in feces of asymptomatic patients admitted to the hospital

EM Terveer, MJT Crobach, IMJG Sanders… - Journal of clinical …, 2017 - Am Soc Microbiol
Recent evidence shows that patients asymptomatically colonized with Clostridium difficile
may contribute to the transmission of C. difficile in health care facilities. Additionally, these …

[HTML][HTML] Clostridium difficile colonization in hematopoietic stem cell transplant recipients: a prospective study of the epidemiology and outcomes involving toxigenic …

T Jain, C Croswell, V Urday-Cornejo, R Awali… - Biology of Blood and …, 2016 - Elsevier
Clostridium difficile is a leading cause of infectious diarrhea in hematopoietic stem cell
transplant (HSCT) recipients. Asymptomatic colonization of the gastrointestinal tract occurs …

[HTML][HTML] Clinical impact of Clostridium difficile colonization

YP Hung, JC Lee, HJ Lin, HC Liu, YH Wu… - Journal of Microbiology …, 2015 - Elsevier
Clostridium difficile can cause antibiotic-associated diarrhea in hospitalized patients.
Asymptomatic colonization by C. difficile is common during the neonatal period and early …