The epithelial cell types and their multi-phased defenses against fungi and other pathogens
K Roe - Clinica Chimica Acta, 2024 - Elsevier
Mucus and its movements are essential to epithelial tissue immune defenses against
pathogens, including fungal pathogens, which can infect respiratory, gastrointestinal or the …
pathogens, including fungal pathogens, which can infect respiratory, gastrointestinal or the …
[HTML][HTML] Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer
JB Finlay, AS Ireland, SB Hawgood, T Reyes, T Ko… - Cancer Cell, 2024 - cell.com
The olfactory epithelium undergoes neuronal regeneration from basal stem cells and is
susceptible to olfactory neuroblastoma (ONB), a rare tumor of unclear origins. Employing …
susceptible to olfactory neuroblastoma (ONB), a rare tumor of unclear origins. Employing …
The Bittersweet Symphony of COVID-19: Associations between TAS1Rs and TAS2R38 Genetic Variations and COVID-19 Symptoms
A Santin, B Spedicati, A Pecori, GG Nardone… - Life, 2024 - mdpi.com
The innate immune system is crucial in fighting SARS-CoV-2 infection, which is responsible
for coronavirus disease 2019 (COVID-19). Therefore, deepening our understanding of the …
for coronavirus disease 2019 (COVID-19). Therefore, deepening our understanding of the …
G protein subunit Gγ13-mediated signaling pathway is critical to the inflammation resolution and functional recovery of severely injured lungs
YH Li, YS Yang, YB Xue, H Lei, SS Zhang, J Qian… - Elife, 2024 - elifesciences.org
Tuft cells are a group of rare epithelial cells that can detect pathogenic microbes and
parasites. Many of these cells express signaling proteins initially found in taste buds. It is …
parasites. Many of these cells express signaling proteins initially found in taste buds. It is …
Human airway tuft cells influence the mucociliary clearance through cholinergic signalling
MI Hollenhorst, T Husnik, M Zylka, N Duda… - Respiratory …, 2023 - Springer
Background Airway tuft cells, formerly called brush cells have long been described only
morphologically in human airways. More recent RNAseq studies described a chemosensory …
morphologically in human airways. More recent RNAseq studies described a chemosensory …
Airway succinate chemosensing induces CFTR-dependent anion secretion and mucus clearance which is impaired in cystic fibrosis.
T Apablaza, M Barros-Poblete, L Delpiano… - bioRxiv, 2024 - biorxiv.org
The respiratory tract possesses a highly regulated innate defense system which includes
efficient cilia-mediated mucus transport or mucociliary clearance (MCC). This essential …
efficient cilia-mediated mucus transport or mucociliary clearance (MCC). This essential …
[PDF][PDF] Ion channels and transporters keep ideas flowing
MK Mansley, P Fong - The Journal of …, 2023 - research-repository.st-andrews.ac …
Ion channels and transporters keep ideas flowing Page 1 This is an Accepted Article that has
been peer-reviewed and approved for publication in the The Journal of Physiology, but has yet …
been peer-reviewed and approved for publication in the The Journal of Physiology, but has yet …