Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …

Ferroptosis is defined as an iron-dependent regulated form of cell death driven by lipid
peroxidation. In the past decade, it has been implicated in the pathogenesis of various …

Ferroptosis is the type of cell death arising from uncontrolled and excessive lipid
peroxidation. NADPH is essential for ferroptosis regulation because it supplies reducing …

Ferroptosis is a form of programmed cell death characterized by elevated intracellular
ferrous ion levels and increased lipid peroxidation. Since its discovery and characterization …

Intracellular redox homeostasis plays an important role in promoting tumor progression,
development and even treatment resistance. To this end, redox balance impairment may …

This article provides an overview of the background knowledge of ferroptosis in the nervous
system, as well as the key role of nuclear factor E2-related factor 2 (Nrf2) in regulating …

Sirtuins, also called silent information regulator 2, are enzymes that rely on nicotinamide
adenine dinucleotide (NAD+) to function as histone deacetylases. Further investigation is …

Cancer cells often exhibit defects in the execution of cell death, resulting in poor clinical
outcomes for patients with many cancer types. Ferroptosis is a newly discovered form of …

Background Ferroptosis was proposed to be a type of programmed cell death in 2012.
Ferroptosis plays a significant role in a variety of illnesses. Objective To better understand …

There is increasing need to expand availability of donor liver grafts, including steatotic livers.
However, the current use of steatotic grafts in liver transplantation is less acceptable due to …