An overview of the current progress, challenges, and prospects of human biomonitoring and exposome studies

MZ Bocato, JP Bianchi Ximenez… - Journal of Toxicology …, 2019 - Taylor & Francis
Human Biomonitoring (HB), the process for determining whether and to what extent
chemical substances penetrated our bodies, serves as a useful tool to quantify human …

Status of metabolomic measurement for insights in Alzheimer's disease progression—What is missing?

C Yin, AC Harms, T Hankemeier, A Kindt… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is an aging-related neurodegenerative disease, leading to the
progressive loss of memory and other cognitive functions. As there is still no cure for AD, the …

[HTML][HTML] Huang-lian-jie-du decoction ameliorates acute ulcerative colitis in mice via regulating NF-κB and Nrf2 signaling pathways and enhancing intestinal barrier …

Z Yuan, L Yang, X Zhang, P Ji, Y Hua… - Frontiers in …, 2019 - frontiersin.org
Evidence shows that intestinal inflammation, oxidative stress, and injury of mucosal barrier
are closely related to the pathogenesis of ulcerative colitis (UC). Huang-lian-Jie-du …

In-depth investigation of the mechanisms of Schisandra chinensis polysaccharide mitigating Alzheimer's disease rat via gut microbiota and feces metabolomics

J Fu, J Li, Y Sun, S Liu, F Song, Z Liu - International Journal of Biological …, 2023 - Elsevier
Schisandra chinensis (S. chinensis) is an herbal medicine used for the treatment of
Alzheimer's disease (AD). The purified polysaccharide fraction, namely SCP2, was …

Traditional Chinese medicine for dementia

S Li, Z Wu, W Le - Alzheimer's & Dementia, 2021 - Wiley Online Library
In Western medicine, dementia refers to a spectrum of diseases affecting cognition, mental
health, and physical abilities. Ancient medical literatures of traditional Chinese medicine …

Huanglian Jiedu decoction remodels the periphery microenvironment to inhibit Alzheimer's disease progression based on the “brain-gut” axis through multiple …

X Gu, J Zhou, Y Zhou, H Wang, N Si, W Ren… - Alzheimer's Research & …, 2021 - Springer
Background In recent years, excellent results have suggested an association between the
“brain-gut” axis and Alzheimer's disease (AD) progression, yet the role of the “brain-gut” axis …

Mechanism of Huang-lian-Jie-du decoction and its effective fraction in alleviating acute ulcerative colitis in mice: Regulating arachidonic acid metabolism and …

Z Yuan, L Yang, X Zhang, P Ji, Y Hua, Y Wei - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Huang-lian-Jie-du decoction (HLJDD) is a
traditional Chinese medicine prescription for clearing away heat, purging fire and …

Vagus nerve stimulated by microbiota‐derived hydrogen sulfide mediates the regulation of berberine on microglia in transient middle cerebral artery occlusion rats

S Ni, ZY Yao, X Wei, X Heng, SY Qu… - Phytotherapy …, 2022 - Wiley Online Library
Amelioration of neuroinflammation via modulating microglia is a promising approach for
cerebral ischemia therapy. The aim of the present study was to explore gut–brain axis …

Huang-Lian Jie-Du decoction: a review on phytochemical, pharmacological and pharmacokinetic investigations

Y Qi, Q Zhang, H Zhu - Chinese Medicine, 2019 - Springer
Abstract Huang-Lian Jie-Du decoction (HLJDD), a famous traditional Chinese prescription
constituted by Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri and Fructus …

UPLC-Q/TOF-MS-Based Serum Metabolomics Reveals Hypoglycemic Effects of Rehmannia glutinosa, Coptis chinensis and Their Combination on High-Fat-Diet …

Z Qin, W Wang, D Liao, X Wu, X Li - International journal of molecular …, 2018 - mdpi.com
Diabetes is a worldwide severe health issue which causes various complications. This study
aimed to evaluate the hypoglycemic effects of Rehmannia glutinosa (RG), Coptis chinensis …