Integrated brain and plasma dual-channel metabolomics to explore the treatment effects of Alpinia oxyphyllaFructus on Alzheimer's disease

Z Sun, Y Zhang, M Zhang, S Zhou, W Cheng, L Xue… - Plos one, 2023 - journals.plos.org
Alpinia oxyphylla Fructus, called Yizhi in Chinese, is the dried fruit of Alpinia oxyphylla
Miquel. It has been used in traditional Chinese medicine to treat dementia and memory …

Liquid Chromatography-Tandem Mass Spectrometry-Based Metabolomics Analysis of Indigo Naturalis Treatment of Ulcerative Colitis in Mice

A Fan, BL Hou, Z Tang, T Wang, D Zhang… - Journal of Medicinal …, 2023 - liebertpub.com
Ulcerative colitis (UC), often known as UC, is an inflammatory disease of the intestines that
has frequent and long-lasting flare-ups. It is unknown precisely how the traditional Chinese …

Integration of 1H NMR-and UPLC-Q-TOF/MS-based plasma metabonomics study to identify diffuse axonal injury biomarkers in rat

P Zhang, S Zhu, M Zhao, Y Dai, L Zhang, S Ding… - Brain Research …, 2018 - Elsevier
Diffuse axonal injury (DAI) is much common during traumatic brain injury (TBI) and is
associated with high mortality and poor neurological outcome. Although many studies have …

Screening of the active Ingredients in Huanglian Jiedu decoction through amide bond-Immobilized magnetic nanoparticle-assisted cell membrane chromatography

F Liao, D He, CT Vong, L Wang, Z Chen… - Frontiers in …, 2022 - frontiersin.org
Introduction: The Huanglian Jiedu decoction (HLJDD) is a Chinese herbal formula that
exerts neuroprotective effects by alleviating oxidative stress injuries and may potentially be …

Strategy of systems biology for visualizing the “Black box” of traditional Chinese medicine

Y Gu, GS Wu, HK Li, WD Zhang - World Journal of Traditional …, 2020 - journals.lww.com
Traditional Chinese medicine (TCM) has been practiced for thousands of years in China.
TCM formula, usually composed of several or even dozens of herbal medicines, is the main …

[PDF][PDF] Integration of multi-omics in investigations on the mechanisms of action of Chinese herbal medicine interventions in metabolic diseases

YJ Cao, HZ Li, YM Sun, XQ Li, L Chen, XW Jin - Tradit Med Res, 2022 - tmrjournals.com
The rapid development of bioinformatics has provided novel approaches and methods for
exploring the mechanisms of disease treatment via Chinese herbal medicines. Compound …

Rapid and accurate simultaneous determination of seven short-chain fatty acids in feces by gas chromatography–mass spectrometry (GC-MS): application in type 2 …

H Wang, Y Liu, J Shao, Y Luo, W Cai, L Chen - Analytical Letters, 2020 - Taylor & Francis
Short-chain fatty acids (SCFAs) are carboxylic acids that contain fewer than six carbons and
are the metabolites of the intestinal flora. SCFAs participate in almost all circulatory system …

Brain metabolomics study for the protective effects of Rhodiola crenulata extract on Alzheimer's disease by HPLC coupled with Fourier transform‐ion cyclotron …

X Li, Y Wang, M Su, X Chu, S Li, Y Yue… - Journal of …, 2020 - Wiley Online Library
In order to investigate the protective effects of Rhodiola crenulata extract on Alzheimer's
disease, a brain metabolomics study in rats was conducted by high performance liquid …

Application of comparative lipidomics to elucidate postprandial metabolic excursions following dairy milk ingestion in individuals with prediabetes

L Chen, S Zhang, X Sun, JD McDonald… - Journal of proteome …, 2021 - ACS Publications
Nutrient-dense dairy foods are an important component of a healthy diet.
Recommendations, however, advise non-and low-fat dairy foods despite controversy …

[PDF][PDF] Network pharmacology-based approach to investigate the mechanism of Huang-Lian-Jie-Du-Decoction for treatment of type 2 diabetes mellitus

HL Li, C Chen, C Chen - Tradit Med Res, 2021 - tmrjournals.com
Background: Although the benefits of Huang-Lian-Jie-Du-Decoction (HLJDD) on type 2
diabetes mellitus are noted, the material base and action mechanism remain unknown. This …