Remodeling tumor microenvironment with natural products to overcome drug resistance

W Zhang, S Li, C Li, T Li, Y Huang - Frontiers in Immunology, 2022 - frontiersin.org
With cancer incidence rates continuing to increase and occurrence of resistance in drug
treatment, there is a pressing demand to find safer and more effective anticancer strategy for …

Polyphenols: bioavailability, microbiome interactions and cellular effects on health in humans and animals

MB Scott, AK Styring, JSO McCullagh - Pathogens, 2022 - mdpi.com
Polyphenolic compounds have a variety of functions in plants including protecting them from
a range of abiotic and biotic stresses such as pathogenic infections, ionising radiation and …

[HTML][HTML] Green extraction of essential oils from Pistacia lentiscus resins: Encapsulation into Niosomes showed improved preferential cytotoxic and apoptotic effects …

SA Fahmy, NK Sedky, A Ramzy… - Journal of Drug Delivery …, 2023 - Elsevier
The essential oils extracted from Pistacia lentiscus resins possess promising antiproliferative
effects against ovarian and breast cancer cells because of their high content of bioactive …

Natural compounds as promising adjuvant agents in the treatment of gliomas

F Persano, G Gigli, S Leporatti - International Journal of Molecular …, 2022 - mdpi.com
In humans, glioblastoma is the most prevalent primary malignant brain tumor. Usually,
glioblastoma has specific characteristics, such as aggressive cell proliferation and rapid …

Chalcones and gastrointestinal cancers: experimental evidence

R Michalkova, M Kello, M Cizmarikova… - International Journal of …, 2023 - mdpi.com
Colorectal (CRC) and gastric cancers (GC) are the most common digestive tract cancers
with a high incidence rate worldwide. The current treatment including surgery …

Fractionation and Characterization of Triterpenoids from Vaccinium vitis-idaea L. Cuticular Waxes and Their Potential as Anticancer Agents

G Vilkickyte, V Petrikaite, M Marksa, L Ivanauskas… - Antioxidants, 2023 - mdpi.com
Fruit and leaf cuticular waxes are valuable source materials for the isolation of triterpenoids
that can be applied as natural antioxidants and anticancer agents. The present study aimed …

Hidden in plants—A review of the anticancer potential of the Solanaceae family in in vitro and in vivo studies

T Kowalczyk, A Merecz-Sadowska, P Rijo, M Mori… - Cancers, 2022 - mdpi.com
Simple Summary The Solanaceae family is one of the most important arable and economic
families in the world. In addition, it includes a wide range of valuable active secondary …

Isobavachalcone: A comprehensive review of its plant sources, pharmacokinetics, toxicity, pharmacological activities and related molecular mechanisms

N Xing, X Meng, S Wang - Phytotherapy Research, 2022 - Wiley Online Library
Isobavachalcone (IBC), also known as isobapsoralcone, is a natural flavonoid widely
derived from many medicinal plants, including Fabaceae, Moraceae, and so forth. IBC has …

Is Caperatic Acid the Only Compound Responsible for Activity of Lichen Platismatia glauca within the Nervous System?

E Studzińska-Sroka, A Majchrzak-Celińska… - Antioxidants, 2022 - mdpi.com
Lichens are a source of various biologically active compounds. However, the knowledge
about them is still scarce, and their use in medicine is limited. This study aimed to investigate …

Anticancer activity of broccoli, its organosulfur and polyphenolic compounds

A Gasmi, A Gasmi Benahmed, M Shanaida… - Critical Reviews in …, 2023 - Taylor & Francis
The use of natural bioactive constituents from various food sources for anticancer purposes
has become increasingly popular worldwide. Broccoli (Brassica oleracea var. italica) is on …