Induction of Ectopic Eyes by Targeted Expression of the eyeless Gene in Drosophila
G Halder, P Callaerts, WJ Gehring - Science, 1995 - science.org
The Drosophila gene eyeless (ey) encodes a transcription factor with both a paired domain
and a homeodomain. It is homologous to the mouse Small eye (Pax-6) gene and to the …
and a homeodomain. It is homologous to the mouse Small eye (Pax-6) gene and to the …
Signaling mechanisms regulating adult neural stem cells and neurogenesis
R Faigle, H Song - Biochimica et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
BACKGROUND: Adult neurogenesis occurs throughout life in discrete regions of the
mammalian brain and is tightly regulated via both extrinsic environmental influences and …
mammalian brain and is tightly regulated via both extrinsic environmental influences and …
MAP kinases
Z Chen, TB Gibson, F Robinson, L Silvestro… - Chemical …, 2001 - ACS Publications
MAP Kinases | Chemical Reviews ACS ACS Publications C&EN CAS Find my institution Log In
Chemical Reviews ACS Publications. Most Trusted. Most Cited. Most Read Quick View Share …
Chemical Reviews ACS Publications. Most Trusted. Most Cited. Most Read Quick View Share …
[PDF][PDF] Pax6 is a human neuroectoderm cell fate determinant
X Zhang, CT Huang, J Chen, MT Pankratz, J Xi, J Li… - Cell stem cell, 2010 - cell.com
The transcriptional regulation of neuroectoderm (NE) specification is unknown. Here we
show that Pax6 is uniformly expressed in early NE cells of human fetuses and those …
show that Pax6 is uniformly expressed in early NE cells of human fetuses and those …
[HTML][HTML] Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
Distinct classes of motor neurons and ventral interneurons are generated by the graded
signaling activity of Sonic hedgehog (Shh). Shh controls neuronal fate by establishing …
signaling activity of Sonic hedgehog (Shh). Shh controls neuronal fate by establishing …
Pallial and subpallial derivatives in the embryonic chick and mouse telencephalon, traced by the expression of the genes Dlx‐2, Emx‐1, Nkx‐2.1, Pax‐6, and Tbr‐1
Pallial and subpallial morphological subdivisions of the developing chicken telencephalon
were examined by means of gene markers, compared with their expression pattern in the …
were examined by means of gene markers, compared with their expression pattern in the …
[HTML][HTML] Pax6 is required for the multipotent state of retinal progenitor cells
T Marquardt, R Ashery-Padan, N Andrejewski… - Cell, 2001 - cell.com
The molecular mechanisms mediating the retinogenic potential of multipotent retinal
progenitor cells (RPCs) are poorly defined. Prior to initiating retinogenesis, RPCs express a …
progenitor cells (RPCs) are poorly defined. Prior to initiating retinogenesis, RPCs express a …
A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.
AT Dudley, KM Lyons, EJ Robertson - Genes & development, 1995 - genesdev.cshlp.org
BMP-7/OP-1, a member of the transforming growth factor-beta (TGF-beta) family of secreted
growth factors, is expressed during mouse embryogenesis in a pattern suggesting potential …
growth factors, is expressed during mouse embryogenesis in a pattern suggesting potential …
Glial cells generate neurons: the role of the transcription factor Pax6
N Heins, P Malatesta, F Cecconi, M Nakafuku… - Nature …, 2002 - nature.com
Radial glial cells, ubiquitous throughout the developing CNS, guide radially migrating
neurons and are the precursors of astrocytes. Recent evidence indicates that radial glial …
neurons and are the precursors of astrocytes. Recent evidence indicates that radial glial …
Eye development and retinogenesis
W Heavner, L Pevny - Cold Spring Harbor perspectives …, 2012 - cshperspectives.cshlp.org
Three embryonic tissue sources—the neural ectoderm, the surface ectoderm, and the
periocular mesenchyme—contribute to the formation of the mammalian eye. For this reason …
periocular mesenchyme—contribute to the formation of the mammalian eye. For this reason …