Atherosclerosis causes significant morbidity and mortality. Carotid intima-media thickness
(CIMT) predicts future cardiovascular and ischaemic stroke incidence. CIMT, a measure of …

Chronic obstructive pulmonary disease (COPD) is independently associated with an
increased burden of cardiovascular disease. Besides coronary artery disease (CAD) and …

BACKGROUND. Understanding the genetic architecture of cardiac structure and function
may help to prevent and treat heart disease. This investigation sought to identify common …

Background A growing number of studies clearly demonstrate a substantial association
between chronic obstructive pulmonary disease (COPD) and cardiovascular diseases …

Cardiovascular disease is a common comorbidity and cause of mortality in chronic
obstructive pulmonary disease. A better understanding of mechanisms of cardiovascular risk …

Background Multiple loci have been identified for coronary artery disease (CAD) by genome-
wide association studies (GWAS), but no such studies on CAD incidence has been reported …

Cardiovascular diseases (CVDs) are the prevalent cause of mortality worldwide. A
combination of environmental and genetic effectors modulates the risk of developing them …

Voltage-gated potassium (Kv) channels each comprise four pore-forming α-subunits that
orchestrate essential duties such as voltage sensing and K+ selectivity and conductance. In …

The KCNE single-span transmembrane subunits are encoded by five-member gene families
in the human and mouse genomes. Primarily recognized for co-assembling with and …

Backgrounds Tobacco smoking is an important risk factor for coronary artery disease (CAD),
but the genetic mechanisms linking smoking to CAD remain largely unknown. Methods We …