The adaptive immune response to influenza virus infection is multifaceted and complex,
involving antibody and cellular responses at both systemic and mucosal levels. Immune …

Seasonal influenza viruses cause recurring global epidemics by continually evolving to
escape host immunity. The viral constraints and host immune responses that limit and drive …

Influenza viruses are respiratory pathogens of public health concern worldwide with up to
650,000 deaths occurring each year. Seasonal influenza virus vaccines are employed to …

Highly effective vaccines elicit specific, robust, and durable adaptive immune responses. To
advance informed vaccine design, it is critical that we understand the cellular dynamics …

Recent approval of mRNA vaccines for emergency use against COVID-19 is likely to
promote rapid development of mRNA-based vaccines targeting a wide range of infectious …

Vaccination is one of the most successful medical interventions that has saved the life of
millions of people. Vaccination is particularly important in patients with multiple myeloma …

Better vaccines against influenza virus are urgently needed to provide broader protection
against diverse strains, subtypes, and types. Such efforts are assisted by the identification of …

Rapidly evolving influenza A viruses (IAVs) and influenza B viruses (IBVs) are major causes
of recurrent lower respiratory tract infections. Current influenza vaccines elicit antibodies …

Influenza viruses remain a severe burden to human health because of their contribution to
overall morbidity and mortality. Current seasonal influenza virus vaccines do not provide …

Seasonal influenza is an annual occurrence, but it is the threat of pandemics that produces
universal concern. Recurring reports of avian influenza viruses severely affecting humans …