5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

Adolescence is a developmental period when physical and cognitive abilities are optimized,
when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal …

Anxiety-like behaviors in mice include social avoidance and avoidance of bright spaces.
Whether these features are distinctly regulated is unclear. We demonstrate that in mice …

The serotonin system modulates a wide variety of emotional behaviors and states, including
reward processing, anxiety, and social interaction. To reveal the underlying patterns of …

Social behaviors are crucial to all mammals. Although the prelimbic cortex (PL, part of
medial prefrontal cortex) has been implicated in social behavior, it is not clear which …

Since our review of central 5-HT receptors and their function twenty years ago, no new 5-HT
receptor has been discovered and there is little evidence that this situation will change in the …

Social memory—the ability to recognize and remember familiar conspecifics—is critical for
the survival of an animal in its social group,. The dorsal CA2 (dCA2),–and ventral CA1 …

Serotonin regulates many physiological processes including sleep, appetite, and mood.
Thus, serotonergic system is an important target in the treatment of psychiatric disorders …

The anterior bed nucleus of the stria terminalis (BNST) has been recognized as a critical
structure in regulating trait anxiety, contextual fear memory, and appetitive behavior, and is …

The role of serotonin in major depressive disorder (MDD) is the focus of accumulating
clinical and preclinical research. The results of these studies reflect the complexity of …