Background It is widely recognized that childhood trauma poses a significant risk of
developing depressive symptoms. However, the underlying mediation mechanism between …

The relationship between adverse childhood experiences (ACEs) and the development of
psychotic symptoms is not well understood. Therefore, this study aimed to investigate the …

Adolescence is marked by the maturation of systems involved in emotional regulation and
by an increased risk for internalizing disorders (anxiety/depression), especially in females …

Depression triggered by harmful stress during adolescence is a common problem that can
affect mental health. To date, the mechanisms underlying this type of depression remain …

Rationale Social stress contributes to the development of depressive and anxiety
symptomatology and promotes pro-inflammatory signaling in the central nervous system. In …

Early childhood adversity increases risk for negative lifelong impacts on health and
wellbeing. Identifying the risk factors and the associated biological adaptations early in life is …

Rationale Social defeat (SD) and cognition have been positioned as features of those at
high-risk of developing psychosis (McCleery and Nuechterlein, 2019; Selten and Cantor …

Com base nos contínuos desenvolvimentos das Terapias Cognitivas, juntamente com o
aporte da Neurociência, a presente pesquisa teve por objetivos evidenciar a influência dos …