Hemostasis encompasses the tightly regulated processes of blood clotting, platelet
activation, and vascular repair. After wounding, the hemostatic system engages a plethora of …

Venous thromboembolism (VTE) encompasses deep-vein thrombosis (DVT) and pulmonary
embolism. VTE is the leading cause of lost disability-adjusted life years and the third leading …

The formation of fibrin clots that are relatively resistant to lysis represents the final step in
blood coagulation. We discuss the genetic and environmental regulators of fibrin structure in …

Venous thrombosis is a leading cause of morbidity and mortality in industrialized countries,
especially in the elderly. Many risk factors have been identified for venous thrombosis that …

Venous thromboembolism (VTE) includes deep vein thrombosis and pulmonary embolism,
and a combination of environmental and genetic risk factors contributes to VTE risk. Within …

Factor V Leiden is a genetic disorder characterized by a poor anticoagulant response to
activated Protein C and an increased risk for venous thromboembolism. Deep venous …

Deep venous thrombosis is a frequent, multifactorial disease and a leading cause of
morbidity and mortality. Most of the time deep venous thrombosis is triggered by the …

Background: Deep vein thrombosis (DVT) is the formation of blood clots (thrombi) in the
deep veins. It commonly affects the deep leg veins (such as the calf veins, femoral vein, or …

It is well known that the ABO blood group exerts a major influence on hemostasis, as O
blood group individuals have lower von Willebrand factor and factor VIII levels than non-O …

Venous thromboembolism is an episodic disease with an annual incidence of 2 to 3/1000
per year that is associated with a high morbidity and mortality. Risk factors for venous …