Pharmacologic therapies in patients with exacerbation of chronic obstructive pulmonary disease: a systematic review with meta-analysis

CC Dobler, AS Morrow, B Beuschel… - Annals of internal …, 2020 - acpjournals.org
Background: Chronic obstructive pulmonary disease (COPD) is characterized by frequent
exacerbations. Purpose: To evaluate the comparative effectiveness and adverse events …

Inhaled versus systemic corticosteroids for acute exacerbations of COPD: a systematic review and meta-analysis

E Papadopoulou, SB Safar, A Khalil… - European …, 2024 - Eur Respiratory Soc
This meta-analysis compares the efficacy and safety of inhaled versus systemic
corticosteroids for COPD exacerbations. Following a pre-registered protocol, we appraised …

Bioinformatics analysis of PLA2G7 as an immune-related biomarker in COPD by promoting expansion and suppressive functions of MDSCs

X Zhao, Y Yue, X Wang, Q Zhang - International immunopharmacology, 2023 - Elsevier
Background Immune mechanism is involved in the pathogenesis of chronic obstructive
pulmonary disease (COPD). However, the exact immune pathogenesis still remains unclear …

Establishment and evaluation of a rat model of sidestream cigarette smoke-induced chronic obstructive pulmonary disease

G Wang, N Mohammadtursun, J Sun, Y Lv… - Frontiers in …, 2018 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a common cause of mortality worldwide.
The current lack of an animal model that can be established within a certain time frame and …

Nebulized corticosteroids in the treatment of COPD exacerbations: systematic review, meta-analysis, and clinical perspective

RA Pleasants, T Wang, X Xu, T Beiko, H Bei… - Respiratory …, 2018 - rc.rcjournal.com
BACKGROUND: COPD guidelines report that systemic corticosteroids are preferred over
inhaled corticosteroids in the treatment of exacerbations, but the inhaled route is considered …

[HTML][HTML] Effect of the asthma–chronic obstructive pulmonary disease syndrome on the stroke, Parkinson's disease, and dementia: a national cohort study

JJ Yeh, YF Wei, CL Lin, WH Hsu - Oncotarget, 2018 - ncbi.nlm.nih.gov
Background To evaluate the association of asthma–chronic obstructive pulmonary disease
syndrome (ACOS) with neurodegenerative diseases (stroke, Parkinson's disease and …

Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease …

Y Yue, B Zhang, Z He, Y Zheng, X Wang… - Frontiers in …, 2024 - frontiersin.org
Objective: Inhaled corticosteroids (ICS) are widely used in chronic obstructive pulmonary
disease (COPD) patients as a treatment option. However, ICS may also increase the risk of …

Nebulized corticosteroids versus systemic corticosteroids for patients with acute exacerbation of chronic obstructive pulmonary disease: A systematic review and meta …

HS Hu, Z Wang, LM Zhao, XD Liu - Frontiers in Pharmacology, 2022 - frontiersin.org
Objective: Systematic comparison of the efficacy and safety of nebulized corticosteroids and
systemic corticosteroids for treating acute exacerbation of chronic obstructive pulmonary …

Inhaled versus systemic corticosteroids for acute exacerbations of COPD: a systematic review and meta-analysis

R Wang, A Corlăteanu, J Vestbo… - European Respiratory …, 2024 - ibn.idsi.md
This meta-analysis compares the efficacy and safety of inhaled versus systemic
corticosteroids for COPD exacerbations. Following a pre-registered protocol, we appraised …

Comparative efficacies of nebulized budesonide and systemic corticosteroids in the treatment of exacerbations of chronic obstructive pulmonary disease: A systematic …

YL Gu, J Pang, ZX Sun, J Hu, Y Sun… - Journal of Clinical …, 2020 - Wiley Online Library
What is known and objective Corticosteroids are recommended by almost all international
guidelines for the management of exacerbations of chronic obstructive pulmonary disease …