Emerging cytotoxic alkaloids in the battle against cancer: Overview of molecular mechanisms

Z Habli, G Toumieh, M Fatfat, ON Rahal… - Molecules, 2017 - mdpi.com
Considered as the second deadliest disease globally, cancer has captured the attention of
researchers who have been trying with perseverance to decode its hidden aspects, to find …

Epidemiology and treatment patterns for locally advanced or metastatic urothelial carcinoma: a systematic literature review and gap analysis

Z Hepp, SN Shah, K Smoyer, P Vadagam - Journal of Managed Care & …, 2021 - jmcp.org
BACKGROUND: Several immuno-oncology (IO) agents targeting programmed death-1 or
programmed death-ligand 1 (PD-1/L1) are approved second-line therapy options for …

Safety and efficacy of atezolizumab in understudied populations with pretreated urinary tract carcinoma: subgroup analyses of the SAUL study in real-world practice

AS Merseburger, D Castellano, T Powles… - The Journal of …, 2021 - auajournals.org
Purpose: Atezolizumab is an established treatment option for pretreated urothelial
carcinoma, demonstrating efficacy in phase II/III trials. The SAUL study enrolled a broader …

Efficacy and safety of chemotherapy regimens in advanced or metastatic bladder and urothelial carcinomas: an updated network meta-analysis

HC Qu, Y Huang, ZY Mu, H Lv, QP Xie… - Frontiers in …, 2020 - frontiersin.org
Background: Gemcitabine plus cisplatin (GC) and methotrexate, vinblastine, adriamycin, and
cisplatin (MVAC) have been the first-line treatments for advanced or metastatic urothelial …

Vinflunine in the treatment of relapsed metastatic urothelial cancer: A systematic review and meta-analysis of real-world series

A Bamias, A Hegele, J Medioni, D Castellano… - Critical Reviews in …, 2019 - Elsevier
Background Vinflunine (VFL) is approved in Europe as second-line treatment of metastatic
urothelial cancer after failure of platinum-containing therapy. We performed a systematic …

Real-life clinical practice results with vinflunine in patients with relapsed platinum-treated metastatic urothelial carcinoma: an Italian multicenter study (MOVIE-GOIRC …

R Passalacqua, S Lazzarelli, M Donini, R Montironi… - BMC cancer, 2017 - Springer
Background Vinflunine is the only chemotherapeutic agent shown to improve survival in
platinum-refractory patients with metastatic transitional cell carcinoma of the urothelium …

Vinflunine in the treatment of upper tract Urothelial carcinoma–subgroup analysis of an observational study

H Heers, P De Geeter, PJ Goebell, U Matz… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Despite an expected prognostic disadvantage for upper tract versus lower
tract metastatic urothelial carcinomas (UTUC/LTUC), only few studies have been conducted …

[HTML][HTML] Maintenance treatment with gemcitabine have a promising activity on metastatic bladder cancer survival

T Kuş, G Aktaş - Turkish Journal of Urology, 2017 - ncbi.nlm.nih.gov
Maintenance treatment with gemcitabine have a promising activity on metastatic bladder cancer
survival - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Vinflunine for the treatment of advanced or metastatic transitional cell carcinoma of the urothelial tract: an evidence-based review of safety, efficacy, and place in …

SC Brousell, JJ Fantony, MG Van Noord… - Core …, 2018 - Taylor & Francis
Background: A systematic review and meta-analysis of the use of systemic vinflunine (VIN)
in the treatment of urothelial carcinoma (UC) was performed to evaluate its efficacy based on …

[HTML][HTML] Atezolizumab plus platinum-based chemotherapy as first-line therapy for metastatic urothelial cancer: A cost-effectiveness analysis

X Liu, Y Lang, Q Chai, Y Lin, Y Liao… - Frontiers in Pharmacology, 2022 - frontiersin.org
Purpose: According to the IMvigor130 trial, adding atezolizumab to platinum-based
chemotherapy was effective in the treatment of metastatic urothelial cancer (mUC). Based on …