The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …

Fibrosis plays an important role in many different pathologies. It results from tissue injury,
chronic inflammation, autoimmune reactions and genetic alterations, and it is characterized …

Purpose To optimize 3D radial ultrashort echo time MRI for high resolution whole‐lung
imaging. Methods 3D radial ultrashort echo time was implemented on a 3T scanner to …

Background MRI of the lung is recommended in a number of clinical indications. Having a
non-radiation alternative is particularly attractive in children and young subjects, or pregnant …

Among current modalities of biomedical and diagnostic imaging, MRI stands out by virtue of
its versatile contrast obtained without ionizing radiation. However, in various cases, eg …

Background One of the central physiological functions of the lungs is to transfer inhaled
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …

Purpose To implement pulmonary three‐dimensional (3D) radial ultrashort echo‐time (UTE)
MRI in non‐sedated, free‐breathing neonates and adults with retrospective motion tracking …

The gravitational gradient of intrapleural pressure is suggested to be less in prone posture
than supine. Thus the gravitational distribution of ventilation is expected to be more uniform …

Purpose Hyperpolarized 129Xe magnetic resonance imaging (MRI) using Dixon‐based
decomposition enables single‐breath imaging of 129Xe in the airspaces, interstitial barrier …

Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …