Purpose The interest in measurements of magnetic resonance imaging relaxation times, T1,
T2, T2*, with intention to characterize healthy and diseased lungs has increased recently …

The Zone model of pulmonary perfusion predicts that exercise reduces perfusion
heterogeneity because increased vascular pressure redistributes flow to gravitationally …

Background: To quantify the relationship between regional lung ventilation and coarse
aerosol deposition in the supine healthy human lung, we used oxygen-enhanced magnetic …

Methods, devices, and systems are disclosed for implementing a fully quantitative non-
injectable contrast proton MRI technique to measure spatial ventilation-perfusion (VA/Q) …

Purpose To demonstrate the feasibility of using octafluorocyclobutane (OFCB, c‐C4F8) for
T1 mapping of lungs in 19F MRI. Methods The study was performed at 7 T in three healthy …

Considerable uncertainty remains about the best ventilator strategies for the mitigation of
atelectasis and associated airspace stretch in patients with acute respiratory distress …

The lung is a dynamic mechanical organ and several pulmonary disorders are characterized
by heterogeneous changes in the lung's local mechanical properties (ie stiffness). These …

Purpose To present a technique, which allows for the in vivo quantification of the spectral
line broadening of the human lung in a single breathhold. The line broadening is an …

Key points The distribution of pulmonary perfusion is affected by gravity, vascular branching
structure and active regulatory mechanisms, which may be disrupted by cardiopulmonary …

Translational investigations in cystic fibrosis (CF) have a need for improved quantitative and
longitudinal measures of disease status. To establish a non-invasive quantitative MRI …