Although it was originally believed that thyroid hormones enter target cells by passive
diffusion, it is now clear that cellular uptake is effected by carrier-mediated processes. Two …

Publisher Summary This chapter reviews the recent advancements in the study of the
transport and metabolism of thyroid hormone. It discusses the role of deiodination …

To get insight in the endocrine and metabolic responses in children with meningococcal
sepsis 26 children were studied the first 48 h after admission. On admission there was a …

Increased lipolysis has been suggested as one of the possible mechanisms underlying
cancer cachexia. The study aim was to assess whether lipolysis is increased in weight …

Liver is an important site for the peripheral production of T3 by outer ring deiodination (ORD)
of T4 as well as for the clearance of plasma rT3, which is produced by inner ring …

Background: The role of gluconeogenesis from protein in the pathogenesis of weight loss in
lung cancer is unclear. Objective: Our aim was to study gluconeogenesis from alanine in …

Objective To investigate the time course of thyroid function, factors that affect it, and its
relationship to outcome in children surviving meningococcal septic shock. Design and …

Summary Background Prader–Willi syndrome (PWS) is a neurogenetic disorder
characterized by muscular hypotonia, psychomotor delay, obesity and short stature. Several …

Nonthyroidal illness (NTI) and fasting in man are characterized by a low serum
concentration of T3 and an increased serum concentration of rT3. Since the serum level of …

Kinetic tracer studies show that thyroid hormones are transported into target tissues by
stereospecific, high-affinity, low-capacity transporters, both in animals and humans. The Kd …