Pharmacological and molecular imaging studies in anxiety disorders have primarily focused
on the serotonin system. In the meantime, dopamine has been known as the …

Animals can choose to act upon, or to ignore, sensory stimuli, depending on circumstance
and prior knowledge. This flexibility is thought to depend on neural inhibition, through …

Aims Epidemiological studies in patients with neuropathic pain have demonstrated a strong
association between neuropathic pain and psychiatric conditions such as anxiety …

Using an innovative approach to study the neural bases of psychiatric disorders, this study
investigated the behavioral, morphological and pharmacological bases of panic attack …

Electrical stimulation of the periaqueductal gray matter and ventromedial hypothalamus in
humans showed the involvement of both these structures in panic attacks. The aim of this …

The effects of endogenous opioid peptide antagonists on panic-related responses are
controversial. Using elevated mazes and a prey-versus-predator paradigm, we investigated …

The neuropsychopharmacological basis of fear‐or panic‐related behavior has been the
focus of several studies. Some mesencephalic tectum (MT) structures, such as the superior …

The potential anxiolytic and antipanic properties of cannabidiol have been shown; however,
its mechanism of action seems to recruit other receptors than those involved in the …

Defensive responses are neurophysiological processes crucial for survival during
threatening situations. Defensive immobility is a common adaptive response, in rodents …

The medial prefrontal cortex can influence unconditioned fear-induced defensive
mechanisms organised by diencephalic neurons that are under tonic GABAergic inhibition …