Background Since the advent of ivermectin (along with melarsomine and doxycycline),
heartworm has come to be viewed as a solved problem in veterinary medicine, diminishing …

Macrocyclic lactones (MLs) are antifilarial drugs. Resistance occurs in Dirofilaria immitis to
the MLs, ivermectin (IVM), milbemycin oxime, selamectin, and moxidectin (MOX). To date …

Filarial parasites of humans and animals represent a heterogeneous group of pathogenic
nematodes, interacting throughout their life cycles with two hosts and, for most species, a …

Despite major similarities in biology and transmission, human and animal filarial parasites
exhibit a number of species‐specific characteristics that prompt the question if a One Health …

The worldwide threat represente d by filarial species has imposed challenging research
initiatives among academic and private contributors toward identifying novel or …