Gram-negative neonatal sepsis in low-and lower-middle-income countries and WHO empirical antibiotic recommendations: A systematic review and meta-analysis

SCH Wen, Y Ezure, L Rolley, G Spurling, CL Lau… - PLoS …, 2021 - journals.plos.org
Background Neonatal sepsis is a significant global health issue associated with marked
regional disparities in mortality. Antimicrobial resistance (AMR) is a growing concern in …

Neonatal sepsis: mortality and morbidity in neonatal sepsis due to multidrug-resistant (MDR) organisms: part 1

C Wattal, N Kler, JK Oberoi, A Fursule, A Kumar… - The Indian Journal of …, 2020 - Springer
The major causes of emergence of multidrug-resistant organisms (MDRO) in neonatal
sepsis include empiric antibiotic prescriptions, unregulated use of over-the-counter drugs …

Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

KL Wyres, TNT Nguyen, MMC Lam, LM Judd… - Genome medicine, 2020 - Springer
Background Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI).
Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are …

Neonatal sepsis in low-income countries: epidemiology, diagnosis and prevention

CR Popescu, MMM Cavanagh, B Tembo… - Expert review of anti …, 2020 - Taylor & Francis
Introduction: Sepsis accounts for up to one-third of neonatal deaths in the world each year.
The World Health Organization acknowledges neonatal sepsis as a major global health …

Pseudomonas aeruginosa: a clinical and genomics update

AC Pelegrin, M Palmieri, C Mirande… - FEMS Microbiology …, 2021 - academic.oup.com
Antimicrobial resistance (AMR) has become a global medical priority that needs urgent
resolution. Pseudomonas aeruginosa is a versatile, adaptable bacterial species with …

Colistin Resistance Among Multiple Sequence Types of Klebsiella pneumoniae Is Associated With Diverse Resistance Mechanisms: A Report From India

M Azam, R Gaind, G Yadav, A Sharma… - Frontiers in …, 2021 - frontiersin.org
Background: The resistance to colistin and carbapenems in Klebsiella pneumoniae
infections have been associated with increased morbidity and mortality worldwide. A …

A road-map for addressing antimicrobial resistance in low-and middle-income countries: lessons learnt from the public private participation and co-designed …

S Singh, E Charani, S Devi, A Sharma… - … Resistance & Infection …, 2021 - Springer
Background The global concern over antimicrobial resistance (AMR) is gathering pace. Low-
and middle-income countries (LMICs) are at the epicentre of this growing public health …

Carbapenem-resistant gram-negative bacterial infections in children

D Aguilera-Alonso, L Escosa-García… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Carbapenem-resistant organisms (CRO) are a major global public health threat.
Enterobacterales hydrolyze almost all β-lactams through carbapenemase production …

Potential antibiotics for the treatment of neonatal sepsis caused by multidrug-resistant bacteria

CA Darlow, RMA da Costa, S Ellis, F Franceschi… - Pediatric Drugs, 2021 - Springer
Neonatal sepsis causes up to an estimated 680,000 deaths annually worldwide,
predominantly in low-and middle-income countries (LMICs). A significant and growing …

Neonatal invasive candidiasis in low-and middle-income countries: data from the NeoOBS study

A Cook, L Ferreras-Antolin, B Adhisivam… - Medical …, 2023 - academic.oup.com
Neonatal invasive candidiasis (NIC) has significant morbidity and mortality. Reports have
shown a different profile of those neonates affected with NIC and of fluconazole-resistant …