Abstract 'Enriched environments' are a key experimental paradigm to decipher how
interactions between genes and environment change the structure and function of the brain …

In the adult mammalian hippocampus, new neurons arise from stem and progenitor cell
division, in a process known as adult neurogenesis. Adult-generated neurons are sensitive …

Exposure to environmental enrichment can beneficially influence the behavior and enhance
synaptic plasticity. The aim of the present study was to investigate the mediated effects of …

Several studies have shown that manipulations to the housing environment modulate
susceptibility to stress in laboratory animals, mainly in rodents. Environmental enrichment …

Stress exposure can produce profound changes in physiology and behavior that can impair
health and well-being. Of note, stress exposure is linked to anxiety disorders and depression …

Mounting evidence shows that physical activity, social interaction and sensorimotor
stimulation provided by environmental enrichment (EE) exert several neurobehavioural …

Depression may be precipitated by the negative impact of chronic stress, which is
considered to play a key role in this neuropsychiatric disorder. Interestingly, depressed …

Environmental enrichment is a widely used experimental manipulation that consistently
shows measurable effects on rodent behaviour across the lifespan. This scoping review …

Human major depressive disorder (MDD), along with related mood disorders, is among the
world's greatest public health concerns; however, its pathophysiology remains poorly …

Depression is a mood disorder coursing with several behavioral, cellular, and
neurochemical alterations. The negative impact of chronic stress may precipitate this …