Objectives: This review addresses the role of central purinergic receptors in the operation of
the cardiovascular reflexes. Methods: Potential physiological role of purinergic receptors …

Adenosine is implicated in the modulation of cardiovascular responses either at the
peripheral or at central level in experimental animals. However, there are no dedicated …

Lumbar (LSNA), renal (RSNA), or adrenal sympathetic nerve activity (ASNA) is most
commonly used as an index of sympathetic nerve activity in investigations of arterial …

Background—The nucleus tractus solitarius (NTS) is the primary integrative center for
baroreflex. Adenosine has been shown to play an important modulatory role in blood …

Selective activation of adenosine A1 and A2a receptors in the subpostremal nucleus tractus
solitarius (NTS) increases and decreases mean arterial pressure (MAP), respectively, and …

Stimulation of nucleus of the solitary tract (NTS) A2a-adenosine receptors elicits
cardiovascular responses quite similar to those observed with rapid, severe hemorrhage …

Baroreflex dysfunction contributes to increased cardiovascular risk in cigarette smokers.
Given the importance of adenosinergic pathways in baroreflex control, the hypothesis was …

Activation of adenosine A2a and ATP P2x purinoceptors in the subpostremal nucleus tractus
solitarii (NTS) via microinjection of the selective agonists CGS-21680 and α, β-methylene …

Previously we showed that pressor and differential regional sympathoexcitatory responses
(adrenal> renal≥ lumbar) evoked by stimulation of A1 adenosine receptors located in the …

Adenosine is a powerful central neuromodulator acting via opposing A1 (inhibitor) and A2a
(activator) receptors. However, in the nucleus of the solitary tract (NTS), both adenosine …