Endometriosis and polycystic ovary syndrome (PCOS) are two common female reproductive
disorders with a significant impact on the health and quality of life of women affected. A …

Kisspeptin is a hypothalamic neuropeptide that acts via the hypothalamus to stimulate
hypothalamic gonadotrophin-releasing hormone secretion and downstream gonadotrophin …

Background Functional placental niches are presumed to spatially separate maternal-fetal
antigens and restrict the vertical transmission of pathogens. We hypothesized a high …

Gestational diseases such as preeclampsia and gestational diabetes cause inflammasome
activation and pyroptosis in the placenta and changes in placental kisspeptin levels …

Kisspeptins (KPs) are proteins that were first recognized to have antimetastatic action. Later,
the critical role of this peptide in the regulation of reproduction was proved. In recent years …

A significant number of pregnancies are lost in the first trimester and 1–2% are ectopic
pregnancies (EPs). Early pregnancy loss in general can cause significant morbidity with …

Brain-derived neurotrophic factor (BDNF) and kisspeptin-1 (KISS-1) regulate placental
development and fetal growth. The predictive value of maternal serum BDNF and KISS-1 …

Kisspeptins, encoded by the KISS1 gene, are a family of polypeptides that bind the
kisspeptin receptor (KISS1R) to perform biological functions. Produced mainly in the …

The objective: to develop a method for predicting the individual risk for great obstetric
syndromes (GOS). Materials and methods. An analysis of the somatic, reproductive, and …

The objective: to establish the risk factors for development of great obstetrical syndromes
(GOS) on the basis of a prospective analysis of somatic, reproductive, obstetric anamnesis in …