Colorectal cancer (CRC) therapy using conventional chemotherapeutics represents a
considerable burden for the patient's organism because of high toxicity while the response is …

An important hallmark in cancer cells is the increase in glucose uptake. GLUT1 is an
important target in cancer treatment because cancer cells upregulate GLUT1, a membrane …

The side-effects and long-term sequelae of anti-cancer chemotherapy remain a major
source of concern for both patients and clinicians despite the improved efficacy and …

The tumor suppressor p53 is one of the most frequently mutated genes in human cancers.
MicroRNAs (miRNAs) are small non-protein coding RNAs that regulate gene expression on …

Natural products or nutraceuticals have been shown to elicit anti-aging, anti-cancer and
other health-enhancing effects. A key target of the effects of natural products may be the …

Worldwide, colorectal cancer (CRC) remains a major cancer type and leading cause of
death. Unfortunately, current medical treatments are not sufficient due to lack of effective …

Combination therapy consists in the simultaneous administration of a conventional
chemotherapy drug (or sometimes, a radiotherapy protocol) together with one or more …

ABSTRACT Introduction: α-Mangostin (α-MG) is the most representative xanthone isolated
from the pericarp of mangosteen, possessing extensive biological activities and …

Natural product compounds have lately attracted interest in the scientific community as a
possible treatment for gastrointestinal (GI) cancer, due to their anti-inflammatory and …

Consumption of coffee, tea, wine, curry, and soybeans has been linked to a lower risk of
cancer in epidemiological studies. Several cell-based and animal studies have shown that …