Vitamin D is known to elicit a vasoprotective effect, while vitamin D deficiency is a risk factor
for endothelial dysfunction (ED). ED is characterized by reduced bioavailability of a potent …

The prevalence of obesity, diabetes, non-alcoholic fatty liver disease, and related metabolic
disorders has been steadily increasing in the past few decades. Apart from the …

Phenolic compounds from marine organisms are far less studied than those from terrestrial
sources since their structural diversity and variability require powerful analytical tools …

Lycopene, a natural pigment that mainly exists in the mature fruit of tomatoes, has gained
increasing attention due to its protective effects against obesity and diabetes. The aim of this …

Allopurinol (ALP) attenuates oxidative stress and diabetic cardiomyopathy (DCM), but the
mechanism is unclear. Activation of nuclear factor erythroid 2‐related factor 2 (Nrf2) …

The global obesity epidemic and the growing elderly population largely contribute to the
increasing incidence of type 2 diabetes. Insulin resistance acts as a critical link between the …

Osteoarthritis (OA) is one of the progressing chronic joint associated with by many complex
factors such as age, obesity, and trauma. Knee osteoarthritis (KOA) is the most common type …

Diabetes mellitus is a metabolic syndrome characterized by increased glucose levels,
oxidative stress, hyperlipidemia, and frequently decreased insulin levels. The current …

Arthritis causes disability due to pain and inflammation in joints. There are many forms of
arthritis, one of which is osteoarthritis whose prevalence increases with age. It occurs in …

Type 2 diabetes mellitus (T2DM) accounts for> 90% of the cases of diabetes in adults.
Resistance to insulin action is the major cause that leads to chronic hyperglycemia in …