Preclinical orofacial pain assays and measures and chronic primary orofacial pain research: where we are and where we need to go

S Sadighparvar, FS Al-Hamed… - Frontiers in Pain …, 2023 - frontiersin.org
Chronic primary orofacial pain (OFP) conditions such as painful temporomandibular
disorders (pTMDs; ie, myofascial pain and arthralgia), idiopathic trigeminal neuralgia (TN) …

The morphology of the mouse masticatory musculature

H Baverstock, NS Jeffery, SN Cobb - Journal of Anatomy, 2013 - Wiley Online Library
The mouse has been the dominant model organism in studies on the development, genetics
and evolution of the mammalian skull and associated soft‐tissue for decades. There is the …

Human and animal experimental models of acute and chronic muscle pain: intramuscular algesic injection

NF Capra, JY Ro - Pain, 2004 - journals.lww.com
Pain of muscle origin is the major presenting symptom of many clinically defined conditions.
Intermittent recurring and chronic pain may be regional (eg temporomandibular disorders …

Different responsiveness of alveolar and tibial bone to bone loss stimuli

A Mavropoulos, R Rizzoli… - Journal of Bone and …, 2007 - academic.oup.com
Mandibular and systemic bone loss are poorly associated. We compared the effect of
isocaloric protein undernutrition and/or ovariectomy on BMD and microstructure of …

Finite element modelling of squirrel, guinea pig and rat skulls: using geometric morphometrics to assess sensitivity

PG Cox, MJ Fagan, EJ Rayfield, N Jeffery - Journal of Anatomy, 2011 - Wiley Online Library
Rodents are defined by a uniquely specialized dentition and a highly complex arrangement
of jaw‐closing muscles. Finite element analysis (FEA) is an ideal technique to investigate …

Rehabilitation of masticatory function improves the alveolar bone architecture of the mandible in adult rats

A Mavropoulos, A Ödman, P Ammann, S Kiliaridis - Bone, 2010 - Elsevier
Masticatory functional changes have been shown to influence the quantity and quality of the
alveolar bone during growth. This study was designed to investigate the effect of masticatory …

Skull Size and Biomechanics are Good Estimators of In Vivo Bite Force in Murid Rodents

S Ginot, A Herrel, J Claude, L Hautier - The Anatomical Record, 2018 - Wiley Online Library
Rodentia is a species‐rich group with diversified modes of life and diets. Although rodent
skull morphology has been the focus of a voluminous literature, the functional significance of …

Biomechanics of a bone–periodontal ligament–tooth fibrous joint

JD Lin, H Özcoban, JP Greene, AT Jang… - Journal of …, 2013 - Elsevier
This study investigates bone–tooth association under compression to identify strain
amplified sites within the bone–periodontal ligament (PDL)–tooth fibrous joint. Our results …

Predicting bite force and cranial biomechanics in the largest fossil rodent using finite element analysis

PG Cox, A Rinderknecht, RE Blanco - Journal of Anatomy, 2015 - Wiley Online Library
Josephoartigasia monesi, from the Pliocene of Uruguay, is the largest known fossil rodent,
with an estimated body mass of 1000 kg. In this study, finite element analysis was used to …

Normal masticatory function partially protects the rat mandibular bone from estrogen-deficiency induced osteoporosis

A Mavropoulos, S Kiliaridis, R Rizzoli… - Journal of Biomechanics, 2014 - Elsevier
Background/aim In a previous study we showed that mandibular alveolar (trabecular) bone
appears to be less sensitive to estrogen deficiency than the proximal tibia spongiosa. We …