Colorectal liver metastasis: molecular mechanism and interventional therapy

H Zhou, Z Liu, Y Wang, X Wen, EH Amador… - Signal transduction and …, 2022 - nature.com
Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …

Modern therapeutic approaches for the treatment of malignant liver tumours

H Petrowsky, R Fritsch, M Guckenberger… - Nature reviews …, 2020 - nature.com
Malignant liver tumours include a wide range of primary and secondary tumours. Although
surgery remains the mainstay of curative treatment, modern therapies integrate a variety of …

[HTML][HTML] ESMO consensus guidelines for the management of patients with metastatic colorectal cancer

E Van Cutsem, A Cervantes, R Adam, A Sobrero… - Annals of …, 2016 - Elsevier
Colorectal cancer (CRC) is one of the most common malignancies in Western countries.
Over the last 20 years, and the last decade in particular, the clinical outcome for patients with …

Local treatment of unresectable colorectal liver metastases: results of a randomized phase II trial

T Ruers, F Van Coevorden, CJA Punt… - JNCI: Journal of the …, 2017 - academic.oup.com
Background Tumor ablation is often employed for unresectable colorectal liver metastases.
However, no survival benefit hasever been demonstrated in prospective randomized …

[HTML][HTML] Colorectal liver metastases: Current management and future perspectives

J Martin, A Petrillo, EC Smyth, N Shaida… - World Journal of …, 2020 - ncbi.nlm.nih.gov
The liver is the commonest site of metastatic disease for patients with colorectal cancer, with
at least 25% developing colorectal liver metastases (CRLM) during the course of their …

The tumor burden score: a new “metro-ticket” prognostic tool for colorectal liver metastases based on tumor size and number of tumors

K Sasaki, D Morioka, S Conci, GA Margonis… - Annals of …, 2018 - journals.lww.com
Objective: To apply the principles of the Metro-ticket paradigm to develop a prognostic
model for patients undergoing hepatic resection of colorectal liver metastasis (CRLM) …

[HTML][HTML] ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making

HJ Schmoll, E Van Cutsem, A Stein, V Valentini… - Annals of oncology, 2012 - Elsevier
Colorectal cancer (CRC) is the most common tumour type in both sexes combined in
Western countries. Although screening programmes including the implementation of faecal …

FOLFOXIRI Plus Panitumumab As First-Line Treatment of RAS Wild-Type Metastatic Colorectal Cancer: The Randomized, Open-Label, Phase II VOLFI Study (AIO …

DP Modest, UM Martens… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE This trial investigated the addition of panitumumab to triplet chemotherapy with
fluorouracil/folinic acid, oxaliplatin, and irinotecan (FOLFOXIRI) in a two-to-one randomized …

Survival after liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors

GP Kanas, A Taylor, JN Primrose… - Clinical …, 2012 - Taylor & Francis
Background Hepatic metastases develop in approximately 50% of colorectal cancer (CRC)
cases. We performed a review and meta-analysis to evaluate survival after resection of CRC …

The oncosurgery approach to managing liver metastases from colorectal cancer: a multidisciplinary international consensus

R Adam, A De Gramont, J Figueras, A Guthrie… - The …, 2012 - academic.oup.com
An international panel of multidisciplinary experts convened to develop recommendations
for the management of patients with liver metastases from colorectal cancer (CRC). The aim …