ABSTRACT The World Health Organization (WHO) has warned that our current arsenal of
antibiotics is not innovative enough to face impending infectious diseases, especially those …

Antibiotic failure is one of the most worrying health problems worldwide. We are currently
facing an international crisis with several problematic facets: new antibiotics are no longer …

Highlights•Biofilm infections are heterogenous, persistent and recalcitrant.•The rise of
antibiotic resistance necessitates new therapeutic strategies to eradicate biofilms.•The …

Antimicrobial resistance (AMR) has become a major problem in public health leading to an
estimated 4.95 million deaths in 2019. The selective pressure caused by the massive and …

Peptide drugs hold great potential for the treatment of infectious diseases due to their
unconventional mechanisms of action, biocompatibility, biodegradability and ease of …

Health care authorities are calling for new antibacterial therapies to cope with the global
emergence of antibiotic-resistant bacteria. Bacteriophage-encoded lysins are a unique class …

Antimicrobial peptides (AMPs) constitute a promising class of alternatives to antibiotics to
curb antimicrobial resistance. Nonetheless, their utility as a systemic agent is hampered by …

The escalating emergence of multidrug-resistant (MDR) pathogens and their ability to
colonize into biofilms on a multitude of surfaces have struck global health as a nightmare …

Bacterial infections are one of the leading causes of death worldwide. In the case of topical
bacterial infections such as wound infections, silver (Ag) has historically been one of the …

Nowadays, bacteriophages are increasingly considered as an alternative treatment for a
variety of bacterial infections in cases where classical antibiotics have become ineffective …