Antimicrobial resistance in enteric bacteria: current state and next-generation solutions

MJ Wallace, SRS Fishbein, G Dantas - Gut microbes, 2020 - Taylor & Francis
Antimicrobial resistance is one of the largest threats to global health and imposes
substantial burdens in terms of morbidity, mortality, and economic costs. The gut is a key …

Advanced engineering of third-generation lysins and formulation strategies for clinical applications

V De Maesschalck, D Gutiérrez… - Critical reviews in …, 2020 - Taylor & Francis
One of the possible solutions for the current antibiotic resistance crisis may be found in
(often bacteriophage-derived) peptidoglycan hydrolases. The first clinical trials of these …

The antibacterial activity of natural-derived flavonoids

Z Tan, J Deng, Q Ye, Z Zhang - Current topics in medicinal …, 2022 - ingentaconnect.com
Flavonoids, a wide variety of phenolic secondary metabolites, are found in almost all plant
families in the leaves, stems, roots, flowers, and seeds. Flavonoids could exert antibacterial …

PEGylated dihydromyricetin-loaded nanoliposomes coated with tea saponin inhibit bacterial oxidative respiration and energy metabolism

F Luo, D Zeng, R Chen, A Zafar, L Weng, W Wang… - Food & Function, 2021 - pubs.rsc.org
The biofilms produced by the aggregation of bacterial colonies are among the major
obstacles of host immune system monitoring and antimicrobial treatment. Herein, we report …

Novel approaches for the treatment of methicillin-resistant Staphylococcus aureus: Using nanoparticles to overcome multidrug resistance

K Vanamala, K Tatiparti, K Bhise, S Sau… - Drug discovery today, 2021 - Elsevier
Highlights•Superbugs such as MRSA are highly prevalent infections with high mortality
rates.•Biofilms and antibiotic resistance impede effective treatment of MRSA.•Conventional …

Facile Synthesis of Self‐Targeted Zn2+‐Gallic acid Nanoflowers for Specific Adhesion and Elimination of Gram‐Positive Bacteria

Y Huang, Y Chen, Z Lu, B Yu, L Zou, X Song, H Han… - Small, 2023 - Wiley Online Library
Transition metal ions are served as disinfectant thousand years ago. However, the in vivo
antibacterial application of metal ions is strongly restricted due to its high affinity with …

Quorum sensing in ESKAPE bugs: a target for combating antimicrobial resistance and bacterial virulence

S Santajit, N Sookrung, N Indrawattana - Biology, 2022 - mdpi.com
Simple Summary Quorum sensing in ESKAPE (Enterococcus faecium, Staphylococcus
aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and …

Paving the way for phage therapy using novel drug delivery approaches

T Briot, C Kolenda, T Ferry, M Medina, F Laurent… - Journal of Controlled …, 2022 - Elsevier
Bacterial resistance against antibiotics is an emergent medical issue. The development of
novel therapeutic approaches is urgently needed and, in this context, bacteriophages …

Plant synthetic biology for producing potent phyto-antimicrobials to combat antimicrobial resistance

P Tiwari, T Khare, V Shriram, H Bae, V Kumar - Biotechnology Advances, 2021 - Elsevier
Inappropriate and injudicious use of antimicrobial drugs in human health, hygiene,
agriculture, animal husbandry and food industries has contributed significantly to rapid …

Multifunctional hydrogel for synergistic reoxygenation and chemo/photothermal therapy in metastatic breast cancer recurrence and wound infection

J Chen, X Zhang, J Zhang, Z Wang, G Zhu… - Journal of Controlled …, 2024 - Elsevier
Metastatic recurrence and postoperative wound infection are two major challenges for
breast cancer patients. In this study, a multifunctional responsive hydrogel system was …