The amyloid cascade hypothesis: an updated critical review

KP Kepp, NK Robakis, PF Høilund-Carlsen, SL Sensi… - Brain, 2023 - academic.oup.com
Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …

Copper in tumors and the use of copper-based compounds in cancer treatment

DA da Silva, A De Luca, R Squitti, M Rongioletti… - Journal of inorganic …, 2022 - Elsevier
Copper homeostasis is strictly regulated by protein transporters and chaperones, to allow its
correct distribution and avoid uncontrolled redox reactions. Several studies address copper …

AIE-based luminescence probes for metal ion detection

P Alam, NLC Leung, J Zhang, RTK Kwok… - Coordination Chemistry …, 2021 - Elsevier
The past two decades have witnessed significant advances in the field of aggregation-
induced emission (AIE). Luminescent materials with AIE characteristics (AIEgens) are of …

Copper homeostasis: Emerging target for cancer treatment

Y Li - IUBMB life, 2020 - Wiley Online Library
Copper (Cu) is an essential micronutrient involved in a variety of fundamental biological
processes. Recently, disorder of Cu homeostasis can be observed in many malignancies …

Enhanced adsorption of Cu (II) and Zn (II) from aqueous solution by polyethyleneimine modified straw hydrochar

X He, T Zhang, Q Xue, Y Zhou, H Wang… - Science of the Total …, 2021 - Elsevier
Heavy metals removal from aqueous phase by adsorption technique has recently attracted a
considerable interest. Although various adsorbing materials have been developed …

Current biomedical use of copper chelation therapy

S Baldari, G Di Rocco, G Toietta - International journal of molecular …, 2020 - mdpi.com
Copper is an essential microelement that plays an important role in a wide variety of
biological processes. Copper concentration has to be finely regulated, as any imbalance in …

Natural Acceptor of Coumarin‐Isomerized Red‐Emissive BioAIEgen for Monitoring Cu2+ Concentration in Live Cells via FLIM

XM Cai, S Li, WJ Wang, Y Lin, W Zhong… - Advanced …, 2024 - Wiley Online Library
Artificial aggregation‐induced emission luminogens (AIEgens) have flourished in bio‐
applications with the development of synthetic chemistry, which however are plagued by …

Simultaneous visualization and quantification of copper (II) ions in Alzheimer's disease by a near-infrared fluorescence probe

Z Zhou, S Chen, Y Huang, B Gu, J Li, C Wu… - Biosensors and …, 2022 - Elsevier
The abnormal accumulation of copper ions (Cu 2+) is considered to be one of the
pathological factors of Alzheimer's disease (AD), but the internal relationship between Cu 2+ …

Copper Imbalance in Alzheimer's Disease: Meta-Analysis of Serum, Plasma, and Brain Specimens, and Replication Study Evaluating ATP7B Gene Variants

R Squitti, M Ventriglia, I Simonelli, C Bonvicini, A Costa… - Biomolecules, 2021 - mdpi.com
Evidence indicates that patients with Alzheimer's dementia (AD) show signs of copper (Cu)
dyshomeostasis. This study aimed at evaluating the potential of Cu dysregulation as an AD …

Review of the design of titanium alloys with low elastic modulus as implant materials

S Liang - Advanced Engineering Materials, 2020 - Wiley Online Library
Herein, an extensive review of the design of titanium alloys with low elastic modulus as
implant materials is provided. Due to the high specific strength, low elastic modulus, fatigue …