Fundamental neurochemistry review: Old brain stories‐Influence of age and sex on the neurodegeneration‐associated lipid changes

L Cuenca‐Bermejo, A Prinetti… - Journal of …, 2023 - Wiley Online Library
Brain aging is a naturally occurring process resulting in the decline of cognitive functions
and increased vulnerability to develop age‐associated disorders. Fluctuation in lipid species …

A detailed review of pathophysiology, epidemiology, cellular and molecular pathways involved in the development and prognosis of Parkinson's disease with insights …

A Sayyaed, N Saraswat, N Vyawahare… - Bulletin of the National …, 2023 - Springer
Background Parkinson's disease is a neurodegenerative disorder of the central nervous
system that is one of the mental disorders that cause tremors, rigidity, and bradykinesia …

Low-dose inhalation exposure to trichloroethylene induces dopaminergic neurodegeneration in rodents

A Adamson, N Ilieva, WJ Stone… - Toxicological …, 2023 - academic.oup.com
Trichloroethylene (TCE) is one of the most pervasive environmental contaminants in the
world and is associated with Parkinson disease (PD) risk. Experimental models in rodents …

Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril …

SL Boyd, NC Kuhn, JR Patterson, AC Stoll… - Toxicological …, 2023 - academic.oup.com
Parkinson's disease (PD) is the fastest-growing neurological disease worldwide, with
increases outpacing aging and occurring most rapidly in recently industrialized areas …

[HTML][HTML] Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration

SA Buck, SA Rubin, T Kunkhyen, CD Treiber, X Xue… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Parkinson's disease (PD) targets some dopamine (DA) neurons more than others. Sex
differences offer insights, with females more protected from DA neurodegeneration. The …

Combating Parkinson's disease with plant-derived polyphenols: Targeting oxidative stress and neuroinflammation

RM Gahtani, S Shoaib, U Hani, R Jayachithra… - Neurochemistry …, 2024 - Elsevier
Parkinson's disease (PD) is a devastating neurodegenerative disorder predominantly
affecting the elderly, characterized by the loss of dopaminergic neurons in the substantia …

Dopamine D2 Receptor Activation Blocks GluA2/ROS Positive Feedback Loop to Alienate Chronic-Migraine-Associated Pain Sensitization

W Zhang, X Zhang, M Lei, D Zhang, G Qin, J Zhou, L Ji… - Antioxidants, 2024 - mdpi.com
Chronic migraine is a disabling disorder without effective therapeutic medicine. AMPA
receptors have been proven to be essential to pathological pain and headaches, but the …

[HTML][HTML] STAT3 protects dopaminergic neurons against degeneration in animal model of Parkinson's disease

RD Smit, B Ghosh, TJ Campion III, R Stingel, E Lavell… - Brain Research, 2024 - Elsevier
Introduction Parkinson's disease (PD) is the most prevalent disorder of the basal ganglia,
propagated by the degeneration of axon terminals within the striatum and subsequent loss …

Chemical toxicity by sex differences: a literature review of 2019–2023 studies

KT Rim - Toxicology and Environmental Health Sciences, 2024 - Springer
Objective and methods While differences in cancer incidence between the two
sexes/genders are often explained by differences in environmental exposure or the …

[HTML][HTML] Developmental origins of Parkinson's disease risk: perinatal exposure to the organochlorine pesticide dieldrin leads to sex-specific DNA modifications in …

J Kochmanski, M Virani, NC Kuhn, SL Boyd, K Becker… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Epidemiological studies show that exposure to the organochlorine pesticide dieldrin is
associated with increased risk of Parkinson's disease (PD). Animal studies support a link …