Over the past decade, cancer diagnosis has expanded to include liquid biopsies in addition
to tissue biopsies. Liquid biopsies can result in earlier and more accurate diagnosis and …

As an emerging sequencing technology, single-cell RNA sequencing (scRNA-Seq) has
become a powerful tool for describing cell subpopulation classification and cell …

Primary triple negative breast cancers (TNBC) are prone to dissemination but sub-clonal
relationships between tumors and resulting metastases are poorly understood. Here we use …

Rationale: Lymphangioleiomyomatosis (LAM) is a metastatic neoplasm of reproductive-age
women associated with mutations in tuberous sclerosis complex genes. LAM causes cystic …

A low-cost microfluidic microarray capable of lysing cells and quantifying proteins released
after lysis was designed and 3D-printed. The array lyses cells on-chip in lysis buffer …

Tumor cells detach from the primary tumor or metastatic sites and enter the peripheral blood,
often causing metastasis. These cells, named Circulating Tumor Cells (CTCs), display the …

Addressing drug resistance is a core challenge in cancer research, but the degree of
heterogeneity in resistance mechanisms in cancer is unclear. In this study, we conducted …

Autoimmunity refers to the phenomenon that the body's immune system produces antibodies
or sensitized lymphocytes to its own tissues to cause an immune response. Immune …

Anticancer target drugs (ATDs) specifically bind and inhibit molecular targets that play
important roles in cancer development and progression, being deeply implicated in …

Single-cell RNA-Seq (scRNA-Seq) has led to an unprecedented understanding of gene
expression and regulation in individual cells. Many scRNA-Seq approaches rely upon the …