[PDF][PDF] Epithelial-mesenchymal plasticity in cancer progression and metastasis
W Lu, Y Kang - Developmental cell, 2019 - cell.com
Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-
epithelial transition (MET), are fundamental processes in embryonic development and tissue …
epithelial transition (MET), are fundamental processes in embryonic development and tissue …
Non-redundant functions of EMT transcription factors
MP Stemmler, RL Eccles, S Brabletz, T Brabletz - Nature cell biology, 2019 - nature.com
Epithelial–mesenchymal transition (EMT) is a crucial embryonic programme that is executed
by various EMT transcription factors (EMT-TFs) and is aberrantly activated in cancer and …
by various EMT transcription factors (EMT-TFs) and is aberrantly activated in cancer and …
[PDF][PDF] Epithelial plasticity, epithelial-mesenchymal transition, and the TGF-β family
Y Katsuno, R Derynck - Developmental cell, 2021 - cell.com
Epithelial cells repress epithelial characteristics and elaborate mesenchymal characteristics
to migrate to other locations and acquire new properties. Epithelial plasticity responses are …
to migrate to other locations and acquire new properties. Epithelial plasticity responses are …
Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities
Epithelial–mesenchymal transition (EMT) is a program wherein epithelial cells lose their
junctions and polarity while acquiring mesenchymal properties and invasive ability …
junctions and polarity while acquiring mesenchymal properties and invasive ability …
Broad applicability of a streamlined ethyl cinnamate-based clearing procedure
Turbidity and opaqueness are inherent properties of tissues that limit the capacity to acquire
microscopic images through large tissues. Creating a uniform refractive index, known as …
microscopic images through large tissues. Creating a uniform refractive index, known as …
Pitx2 patterns an accelerator-brake mechanical feedback through latent TGFβ to rotate the gut
BD Sanketi, N Zuela-Sopilniak, E Bundschuh, S Gopal… - Science, 2022 - science.org
The vertebrate intestine forms by asymmetric gut rotation and elongation, and errors cause
lethal obstructions in human infants. Rotation begins with tissue deformation of the dorsal …
lethal obstructions in human infants. Rotation begins with tissue deformation of the dorsal …
Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation
S Thériault, Z Li, E Abner, J Luan… - Nature …, 2024 - nature.com
There is currently no medical therapy to prevent calcific aortic valve stenosis (CAVS). Multi-
omics approaches could lead to the identification of novel molecular targets. Here, we …
omics approaches could lead to the identification of novel molecular targets. Here, we …
Left-right asymmetry in heart development and disease: forming the right loop
A Desgrange, JF Le Garrec, SM Meilhac - Development, 2018 - journals.biologists.com
Extensive studies have shown how bilateral symmetry of the vertebrate embryo is broken
during early development, resulting in a molecular left-right bias in the mesoderm. However …
during early development, resulting in a molecular left-right bias in the mesoderm. However …
Prrx1b restricts fibrosis and promotes Nrg1-dependent cardiomyocyte proliferation during zebrafish heart regeneration
DEM de Bakker, M Bouwman, E Dronkers… - …, 2021 - journals.biologists.com
Fibroblasts are activated to repair the heart following injury. Fibroblast activation in the
mammalian heart leads to a permanent fibrotic scar that impairs cardiac function. In other …
mammalian heart leads to a permanent fibrotic scar that impairs cardiac function. In other …
A gene regulatory network to control EMT programs in development and disease
Abstract The Epithelial to Mesenchymal Transition (EMT) regulates cell plasticity during
embryonic development and in disease. It is dynamically orchestrated by transcription …
embryonic development and in disease. It is dynamically orchestrated by transcription …