Experimental in vitro, ex vivo and in vivo models in prostate cancer research
V Sailer, G von Amsberg, S Duensing, J Kirfel… - Nature Reviews …, 2023 - nature.com
Androgen deprivation therapy has a central role in the treatment of advanced prostate
cancer, often causing initial tumour remission before increasing independence from signal …
cancer, often causing initial tumour remission before increasing independence from signal …
Current knowledge about the impact of microgravity on gene regulation
Microgravity (µ g) has a massive impact on the health of space explorers. Microgravity
changes the proliferation, differentiation, and growth of cells. As crewed spaceflights into …
changes the proliferation, differentiation, and growth of cells. As crewed spaceflights into …
Recent advances in thyroid cancer research
D Grimm - International Journal of Molecular Sciences, 2022 - mdpi.com
This Special Issue (SI)“Recent Advances in Thyroid Cancer Research” covers research
articles and reviews in the field of thyroid cancer research. It includes publications reporting …
articles and reviews in the field of thyroid cancer research. It includes publications reporting …
Extraterrestrial gynecology: could spaceflight increase the risk of developing cancer in female astronauts? An updated review
R Drago-Ferrante, R Di Fiore, F Karouia… - International journal of …, 2022 - mdpi.com
Outer space is an extremely hostile environment for human life, with ionizing radiation from
galactic cosmic rays and microgravity posing the most significant hazards to the health of …
galactic cosmic rays and microgravity posing the most significant hazards to the health of …
Decellularized plant-derived vasculature-on-a-chip interacting with breast cancer spheroids to evaluate a dual-drug therapy
Y Filiz, Y Arslan, E Duran, P Saglam-Metiner… - Applied Materials …, 2024 - Elsevier
Breast cancer progression is a complex process involving the primary tumor and its
microenvironment supported by a vascular network. Multicellular spheroids closely mimic in …
microenvironment supported by a vascular network. Multicellular spheroids closely mimic in …
Impairment of 7F2 osteoblast function by simulated partial gravity in a Random Positioning Machine
J Braveboy-Wagner, PI Lelkes - NPJ microgravity, 2022 - nature.com
The multifaceted adverse effects of reduced gravity pose a significant challenge to human
spaceflight. Previous studies have shown that bone formation by osteoblasts decreases …
spaceflight. Previous studies have shown that bone formation by osteoblasts decreases …
Simulated microgravity influences immunity-related biomarkers in lung cancer
Microgravity is a novel strategy that may serve as a complementary tool to develop future
cancer therapies. In lung cancer, the influence of microgravity on cellular processes and the …
cancer therapies. In lung cancer, the influence of microgravity on cellular processes and the …
3D-Printed Tumor-on-a-Chip Model for Investigating the Effect of Matrix Stiffness on Glioblastoma Tumor Invasion
Glioblastoma multiform (GBM) tumor progression has been recognized to be correlated with
extracellular matrix (ECM) stiffness. Dynamic variation of tumor ECM is primarily regulated …
extracellular matrix (ECM) stiffness. Dynamic variation of tumor ECM is primarily regulated …
Long-term simulation of microgravity induces changes in gene expression in breast cancer cells
J Sahana, JL Cortés-Sánchez, V Sandt… - International Journal of …, 2023 - mdpi.com
Microgravity changes the gene expression pattern in various cell types. This study focuses
on the breast cancer cell lines MCF-7 (less invasive) and MDA-MB-231 (triple-negative …
on the breast cancer cell lines MCF-7 (less invasive) and MDA-MB-231 (triple-negative …
Metabolomics Profile of the Secretome of Space-Flown Oligodendrocytes
L Vergnes, B Foucaud, C Cepeda, A Espinosa-Jeffrey - Cells, 2023 - mdpi.com
Intracranial hypertension (ICP) and visual impairment intracranial pressure (VIIP) are some
of the sequels of long-term space missions. Here we sought to determine how space …
of the sequels of long-term space missions. Here we sought to determine how space …