Antimicrobial peptides: Application informed by evolution

BP Lazzaro, M Zasloff, J Rolff - Science, 2020 - science.org
BACKGROUND Antimicrobial peptides (AMPs) are small proteins with potent antibacterial,
antiviral, and antifungal activity. AMPs are ubiquitous among multicellular eukaryotes, with …

[HTML][HTML] Plant antimicrobial peptides: structures, functions, and applications

J Li, S Hu, W Jian, C Xie, X Yang - Botanical Studies, 2021 - Springer
Antimicrobial peptides (AMPs) are a class of short, usually positively charged polypeptides
that exist in humans, animals, and plants. Considering the increasing number of drug …

[HTML][HTML] Plant disease resistance-related signaling pathways: recent progress and future prospects

LN Ding, YT Li, YZ Wu, T Li, R Geng, J Cao… - International Journal of …, 2022 - mdpi.com
Plant–pathogen interactions induce a signal transmission series that stimulates the plant's
host defense system against pathogens and this, in turn, leads to disease resistance …

[HTML][HTML] Antimicrobial peptides: from design to clinical application

C Zhang, M Yang - Antibiotics, 2022 - mdpi.com
Infection of multidrug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …

In pursuit of next-generation therapeutics: Antimicrobial peptides against superbugs, their sources, mechanism of action, nanotechnology-based delivery, and clinical …

A Thakur, A Sharma, HK Alajangi, PK Jaiswal… - International Journal of …, 2022 - Elsevier
Antimicrobial peptides (AMPs) attracted attention as potential source of novel antimicrobials.
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …

[HTML][HTML] Combating bovine mastitis in the dairy sector in an era of antimicrobial resistance: ethno-veterinary medicinal option as a viable alternative approach

DJ Ajose, BO Oluwarinde, TO Abolarinwa… - Frontiers in veterinary …, 2022 - frontiersin.org
Bovine mastitis (BM) is the traditional infectious condition in reared cattle which may result in
serious repercussions ranging from animal welfare to economic issues. Owing to the high …

[HTML][HTML] Plant antimicrobial peptides: An overview about classification, toxicity and clinical applications

AM Lima, MIG Azevedo, LM Sousa, NS Oliveira… - International journal of …, 2022 - Elsevier
Antimicrobial peptides, also known as AMPs, are cationic and amphipathic molecules found
in all living organisms, composing part of the defense mechanisms against various …

[HTML][HTML] Immunomodulatory peptides—A promising source for novel functional food production and drug discovery

M Pavlicevic, N Marmiroli, E Maestri - Peptides, 2022 - Elsevier
Immunomodulatory peptides are a complex class of bioactive peptides that encompasses
substances with different mechanisms of action. Immunomodulatory peptides could also be …

Genome-Wide Identification of Tomato Xylem Sap Fitness Factors for Three Plant-Pathogenic Ralstonia Species

SJ Georgoulis, KE Shalvarjian, TC Helmann… - Msystems, 2021 - Am Soc Microbiol
Plant-pathogenic Ralstonia spp. colonize plant xylem and cause wilt diseases on a broad
range of host plants. To identify genes that promote growth of diverse Ralstonia strains in …

[HTML][HTML] Expression strategies for the efficient synthesis of antimicrobial peptides in plastids

MP Hoelscher, J Forner, S Calderone, C Krämer… - Nature …, 2022 - nature.com
Antimicrobial peptides (AMPs) kill microbes or inhibit their growth and are promising next-
generation antibiotics. Harnessing their full potential as antimicrobial agents will require …