The inter-relationship between delirium and dementia: the importance of delirium prevention

TG Fong, SK Inouye - Nature Reviews Neurology, 2022 - nature.com
Delirium and dementia are two frequent causes of cognitive impairment among older adults
and have a distinct, complex and interconnected relationship. Delirium is an acute …

Biological functions of lymphatic vessels

TV Petrova, GY Koh - Science, 2020 - science.org
BACKGROUND Blood and lymphatic vessel networks form two arms of the vertebrate
cardiovascular system that play complementary roles in body homeostasis maintenance and …

Diagnosis of Alzheimer's disease utilizing amyloid and tau as fluid biomarkers

JC Lee, SJ Kim, S Hong, YS Kim - Experimental & molecular medicine, 2019 - nature.com
Current technological advancements in clinical and research settings have permitted a more
intensive and comprehensive understanding of Alzheimer's disease (AD). This development …

Biomarkers used in Alzheimer's disease diagnosis, treatment, and prevention

YAR Mahaman, KS Embaye, F Huang, L Li, F Zhu… - Ageing research …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), being the number one in terms of dementia burden, is an
insidious age-related neurodegenerative disease and is presently considered a global …

At the interface of sensory and motor dysfunctions and Alzheimer's disease

MW Albers, GC Gilmore, J Kaye, C Murphy… - Alzheimer's & …, 2015 - Elsevier
Recent evidence indicates that sensory and motor changes may precede the cognitive
symptoms of Alzheimer's disease (AD) by several years and may signify increased risk of …

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

JM Castellano, J Kim, FR Stewart, H Jiang… - Science translational …, 2011 - science.org
The apolipoprotein E (APOE) ε4 allele is the strongest genetic risk factor for late-onset,
sporadic Alzheimer's disease (AD). The APOE ε4 allele markedly increases AD risk and …

[HTML][HTML] Diagnostic biomarkers of Alzheimer's disease: a state-of-the-art review

R Khoury, E Ghossoub - Biomarkers in Neuropsychiatry, 2019 - Elsevier
In 2018, there was a recent shift towards a biological definition of Alzheimer's disease (AD),
based on biomarkers measured in vivo even before the onset of clinical dementia …

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

K Blennow, H Hampel, M Weiner… - Nature Reviews …, 2010 - nature.com
Intense multidisciplinary research has provided detailed knowledge of the molecular
pathogenesis of Alzheimer disease (AD). This knowledge has been translated into new …

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the …

P Lewczuk, P Riederer, SE O'bryant… - The world journal of …, 2018 - Taylor & Francis
In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

LM Shaw, H Vanderstichele… - Annals of …, 2009 - Wiley Online Library
Objective Develop a cerebrospinal fluid biomarker signature for mild Alzheimer's disease
(AD) in Alzheimer's Disease Neuroimaging Initiative (ADNI) subjects. Methods Amyloid‐β 1 …