Biomaterials elicit pyroptosis enhancing cancer immunotherapy

MJ Zhang, YY Wang, LL Han, XY Liu… - Advanced Functional …, 2024 - Wiley Online Library
Cancer immunotherapy has the potential to revolutionize the treatment of malignant tumors,
but its effectiveness is limited by the low immune response rate and immune‐related …

Hyperthermia–embolization–immunotherapy: a potent trio in advancing cancer treatment

R Zaman, X Cai, QTH Shubhra - Trends in Molecular Medicine, 2023 - cell.com
Yang et al. recently demonstrated the high potential of liquid metal microspheres (LM MSs)
in cancer therapy. By amplifying the effects of magnetic hyperthermia and embolization, LM …

Hyaluronic acid-empowered nanotheranostics in breast and lung cancers therapy

F Alsaikhan - Environmental Research, 2023 - Elsevier
Nanomedicine application in cancer therapy is an urgency because of inability of current
biological therapies for complete removal of tumor cells. The development of smart and …

Targeting pyroptosis in breast cancer: Biological functions and therapeutic potentials on It

C Chen, Q Ye, L Wang, J Zhou, A Xiang, X Lin… - Cell death …, 2023 - nature.com
Pyroptosis is a lytic and inflammatory type of programmed cell death that is mediated by
Gasdermin proteins (GSDMs). Attractively, recent evidence indicates that pyroptosis involves …

At the crossroad of nanotechnology and cancer cell membrane coating: Expanding horizons with engineered nanoplatforms for advanced cancer therapy harnessing …

H Pan, S Yang, L Gao, J Zhou, W Cheng… - Coordination Chemistry …, 2024 - Elsevier
The development of targeted drug delivery systems (DDSs) has revolutionized cancer
therapy by improving the selectivity of drug delivery to cancer cells, thereby reducing …

Alternate-day fasting exacerbates doxorubicin cardiotoxicity in cancer chemotherapy

H Pan, S Yang, W Cheng, Q Cai… - Trends in Endocrinology & …, 2023 - cell.com
Doxorubicin (Dox) is a highly potent chemotherapy drug. Despite its efficacy, Dox's clinical
application is limited due to its association with significant complications, namely …

Enhanced therapeutic efficacy of doxorubicin against multidrug-resistant breast cancer with reduced cardiotoxicity

T Zhang, N Li, R Wang, Y Sun, X He, X Lu, L Chu… - Drug Delivery, 2023 - Taylor & Francis
Doxorubicin (DOX), a commonly used anti-cancer drug, is limited by its cardiotoxicity and
multidrug resistance (MDR) of tumor cells. Epigallocatechin gallate (EGCG), a natural …

Biodegradable triboelectric nanogenerator as a implantable power source for embedded medicine devices

G Jian, S Zhu, X Yuan, S Fu, N Yang, C Yan… - NPG Asia …, 2024 - nature.com
Implantable medical devices have played an important role in human medicine in recent
decades. However, traditional implanted devices require battery replacement and a second …

Targeting metabolic circuitry to supercharge CD8+ T cell antitumor responses

Q Cai, Y Tian, QTH Shubhra - Cell Metabolism, 2024 - Elsevier
Tumors compromise T cell functionality through various mechanisms, including the induction
of a nutrient-scarce microenvironment, leading to lipid accumulation and metabolic …

Targeting Lysosome for Enhanced Cancer Photodynamic/Photothermal Therapy in a “One Stone Two Birds” Pattern

Q Sun, J Yang, Q Wu, W Shen, Y Yang… - ACS Applied Materials & …, 2023 - ACS Publications
Highly immunogenic programmed death of tumor cells, such as immunogenic cell death
(ICD) and pyroptosis, strengthens antitumor responses and thus represents a promising …