New approaches to chronic hepatitis B
G Dusheiko, K Agarwal, MK Maini - New England Journal of …, 2023 - Mass Medical Soc
New Approaches to Chronic Hepatitis B | New England Journal of Medicine Skip to main content
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[HTML][HTML] From hepatitis A to E: A critical review of viral hepatitis
Viral infections affecting the liver have had an important impact on humanity, as they have
led to significant morbidity and mortality in patients with acute and chronic infections. Once …
led to significant morbidity and mortality in patients with acute and chronic infections. Once …
Hepatitis B virus-associated hepatocellular carcinoma
Hepatitis B virus (HBV) is DNA-based virus, member of the Hepadnaviridae family, which
can cause liver disease and increased risk of hepatocellular carcinoma (HCC) in infected …
can cause liver disease and increased risk of hepatocellular carcinoma (HCC) in infected …
Viral hepatitis and pregnancy
NA Terrault, MT Levy, KW Cheung… - Nature reviews …, 2021 - nature.com
The management of viral hepatitis in the setting of pregnancy requires special consideration.
There are five liver-specific viruses (hepatitis A, B, C, D, E), each with unique epidemiology …
There are five liver-specific viruses (hepatitis A, B, C, D, E), each with unique epidemiology …
HBV-integration studies in the clinic: role in the natural history of infection
T Pollicino, G Caminiti - Viruses, 2021 - mdpi.com
Hepatitis B virus (HBV) infection is a major global health problem causing acute and chronic
liver disease that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). HBV …
liver disease that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). HBV …
[HTML][HTML] The role of cGAS-STING signalling in liver diseases
R Chen, J Du, H Zhu, Q Ling - Jhep Reports, 2021 - Elsevier
The recently identified novel cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS)
activates the downstream adaptor protein stimulator of interferon genes (STING) by …
activates the downstream adaptor protein stimulator of interferon genes (STING) by …
[HTML][HTML] Potential of cell-penetrating peptides (CPPs) in delivery of antiviral therapeutics and vaccines
Viral infections are a great threat to human health. Currently, there are no effective vaccines
and antiviral drugs against the majority of viral diseases, suggesting the need to develop …
and antiviral drugs against the majority of viral diseases, suggesting the need to develop …
Comprehensive analysis of clinically significant hepatitis B virus mutations in relation to genotype, subgenotype and geographic region
Hepatitis B virus (HBV) is a highly variable DNA virus due to its unique life cycle, which
involves an error-prone reverse transcriptase. The high substitution rate drives the evolution …
involves an error-prone reverse transcriptase. The high substitution rate drives the evolution …
[HTML][HTML] De novo synthesis of hepatitis B virus nucleocapsids is dispensable for the maintenance and transcriptional regulation of cccDNA
Background & Aims Chronic HBV infection cannot be cured by current therapeutics owing to
their limited ability to reduce covalently closed circular (ccc) DNA levels in the livers of …
their limited ability to reduce covalently closed circular (ccc) DNA levels in the livers of …
Hepatitis B virus DNA integration, chronic infections and hepatocellular carcinoma
Hepatitis B Virus (HBV) is an Old World virus with a high mutation rate, which puts its origins
in Africa alongside the origins of Homo sapiens, and is a member of the Hepadnaviridae …
in Africa alongside the origins of Homo sapiens, and is a member of the Hepadnaviridae …