A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations
The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
Pirfenidone: molecular mechanisms and potential clinical applications in lung disease
SM Ruwanpura, BJ Thomas… - American journal of …, 2020 - atsjournals.org
Pirfenidone (PFD) is a pharmacological compound with therapeutic efficacy in idiopathic
pulmonary fibrosis. It has been chiefly characterized as an antifibrotic agent, although it was …
pulmonary fibrosis. It has been chiefly characterized as an antifibrotic agent, although it was …
Evaluation of potential toxicity of polyethylene microplastics on human derived cell lines
R Gautam, JH Jo, M Acharya, A Maharjan… - Science of the Total …, 2022 - Elsevier
Microplastics bare of major concern for environmental conservation and animal welfare in
recent years as its use has increased tremendously. Polyethylene microplastics (PE-MPs) …
recent years as its use has increased tremendously. Polyethylene microplastics (PE-MPs) …
Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation
Inhibitors of VEGF (vascular endothelial growth factor)/VEGFR2 (vascular endothelial growth
factor receptor 2) are commonly used in the clinic, but their beneficial effects are only …
factor receptor 2) are commonly used in the clinic, but their beneficial effects are only …
[HTML][HTML] SARS-CoV-2–associated ssRNAs activate inflammation and immunity via TLR7/8
V Salvi, HO Nguyen, F Sozio, T Schioppa, C Gaudenzi… - JCI insight, 2021 - ncbi.nlm.nih.gov
The inflammatory and IFN pathways of innate immunity play a key role in the resistance and
pathogenesis of coronavirus disease 2019 (COVID-19). Innate sensors and SARS-CoV-2 …
pathogenesis of coronavirus disease 2019 (COVID-19). Innate sensors and SARS-CoV-2 …
[HTML][HTML] Pas de deux: control of anti-tumor immunity by cancer-associated inflammation
S Shalapour, M Karin - Immunity, 2019 - cell.com
In many settings, tumor-associated inflammation, supported mainly by innate immune cells,
contributes to tumor growth. Initial innate activation triggers secretion of inflammatory …
contributes to tumor growth. Initial innate activation triggers secretion of inflammatory …
The importance of dendritic cells in maintaining immune tolerance
C Audiger, MJ Rahman, TJ Yun, KV Tarbell… - The Journal of …, 2017 - journals.aai.org
Immune tolerance is necessary to prevent the immune system from reacting against self, and
thus to avoid the development of autoimmune diseases. In this review, we discuss key …
thus to avoid the development of autoimmune diseases. In this review, we discuss key …
FcγR engagement reprograms neutrophils into antigen cross-presenting cells that elicit acquired anti-tumor immunity
Classical dendritic cells (cDC) are professional antigen-presenting cells (APC) that regulate
immunity and tolerance. Neutrophil-derived cells with properties of DCs (nAPC) are …
immunity and tolerance. Neutrophil-derived cells with properties of DCs (nAPC) are …
Biology of interleukin-10
R Sabat, G Grütz, K Warszawska, S Kirsch… - Cytokine & growth factor …, 2010 - Elsevier
Interleukin (IL)-10 is the most important cytokine with anti-inflammatory properties besides
TGF-β and IL-35. It is produced by activated immune cells, in particular monocytes …
TGF-β and IL-35. It is produced by activated immune cells, in particular monocytes …
Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy
Abstract Interleukin-10 (IL-10) is arguably the most potent anti-inflammatory cytokine. It is
produced by almost all the innate and adaptive immune cells. These cells also serve as its …
produced by almost all the innate and adaptive immune cells. These cells also serve as its …