Emerging trends in neoadjuvant chemotherapy for ovarian cancer

A Patel, P Iyer, S Matsuzaki, K Matsuo, AK Sood… - Cancers, 2021 - mdpi.com
Simple Summary Epithelial ovarian cancer is one of the most lethal cancers in women and is
typically diagnosed at an advanced-stage. Historically, primary tumor reductive surgery was …

Ovarian cancer recurrence and early detection: may HE4 play a key role in this open challenge? A systematic review of literature

S Capriglione, D Luvero, F Plotti, C Terranova… - Medical Oncology, 2017 - Springer
Despite the improvement in overall survival for ovarian cancer (OC) patients, a fraction of
patients with advanced-stage disease fails to respond to primary therapy and relapses in …

Through the looking glass: updated insights on ovarian cancer diagnostics

S Chakraborty, PS Shenoy, M Mehrotra, P Phadte… - Diagnostics, 2023 - mdpi.com
Epithelial ovarian cancer (EOC) is the deadliest gynaecological malignancy and the eighth
most prevalent cancer in women, with an abysmal mortality rate of two million worldwide …

Evaluation of patients with advanced epithelial ovarian cancer before primary treatment: correlation between tumour burden assessed by [18F]FDG PET/CT …

A Glickman, P Paredes, N Carreras-Diéguez… - European …, 2022 - Springer
Objectives Accurate assessment of disease extent is required to select the best primary
treatment for advanced epithelial ovarian cancer patients. Estimation of tumour burden is …

Sarcopenia in ovarian cancer patients, oncologic outcomes revealing the importance of clinical nutrition: review of literature

S Cianci, V Rumolo, A Rosati, G Scaletta… - Current …, 2019 - ingentaconnect.com
Introduction: Ovarian cancer is the leading cause of death among gynecological
malignancies. Its usual clinical manifestation is at advanced stages, with nutritional …

Prognostic value of HE4 in advanced-stage, high-grade serous ovarian cancer: Analysis of HE4 kinetics during NACT, predicting surgical outcome and recurrence in …

A AlSomairi, S Himayda, A Altelmesani, YJ Lee… - Gynecologic …, 2024 - Elsevier
Objectives To assess the prognostic value of human epididymis protein 4 (HE4) kinetics
during and after neoadjuvant chemotherapy (NACT) cycles compared with cancer antigen …

CA-125 elimination rate constant K (KELIM) as a promising predictor of complete cytoreduction after neoadjuvant chemotherapy in advanced ovarian cancer patients …

C Li, Q Cui, X Wang, S Yao, H Tu, M Chen - BMC cancer, 2024 - Springer
Background The modeled CA-125 elimination constant K (KELIM) is a potential marker of
tumor chemosensitivity in ovarian cancer patients treated with neoadjuvant chemotherapy …

Management of postoperative chylous ascites after surgery for ovarian cancer: a single-institution experience

G Scaletta, L Quagliozzi, S Cianci, V Vargiu, MC Mele… - Updates in Surgery, 2019 - Springer
Postoperative chylous ascites is a rare complication from operative trauma to the cisterna
chyli or lymphatic vessels in the retroperitoneum. In the present study, we aimed to identify …

HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells

NE James, E Cantillo, MT Oliver… - Clinical & …, 2018 - academic.oup.com
Ovarian cancers are known to evade immunosurveillance and to orchestrate a suppressive
immune microenvironment. Here we examine the role of human epididymis protein 4 (HE4) …

Identification of ovarian cancer patients most likely to achieve chemotherapy response score 3 following neoadjuvant chemotherapy: development of a predictive …

W Liang, H Li, JY Wu, C Liu, MF Wu, J Li - Frontiers in Oncology, 2020 - frontiersin.org
Background: The chemotherapy response score (CRS) system is a reproducible prognostic
tool for patients receiving neoadjuvant chemotherapy (NACT) for tubo-ovarian high-grade …