Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Revisiting the role of neurotransmitters in epilepsy: An updated review

E Akyuz, AK Polat, E Eroglu, I Kullu, E Angelopoulou… - Life sciences, 2021 - Elsevier
Epilepsy is a neurologicaldisorder characterized by persistent predisposition to recurrent
seizurescaused by abnormal neuronal activity in the brain. Epileptic seizures maydevelop …

Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression

D Huang, Y Wang, JW Thompson, T Yin… - Nature cell …, 2022 - nature.com
Many cancers have an unusual dependence on glutamine. However, most previous studies
have focused on the contribution of glutamine to metabolic building blocks and the energy …

Tumor innervation: peripheral nerves take control of the tumor microenvironment

SM Gysler, R Drapkin - The Journal of clinical investigation, 2021 - Am Soc Clin Investig
In recent decades, cancer research has expanded exponentially beyond the study of
abnormally dividing cells to include complex and extensive heterotypic interactions between …

Critical neurotransmitters in the neuroimmune network

TW Hodo, MTP De Aquino, A Shimamoto… - Frontiers in …, 2020 - frontiersin.org
Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …

[HTML][HTML] Role of serotonin receptor signaling in cancer cells and anti-tumor immunity

S Karmakar, G Lal - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter known to affect
emotion, behavior, and cognition, and its effects are mostly studied in neurological diseases …

Role of the nervous system in cancers: a review

H Wang, Q Zheng, Z Lu, L Wang, L Ding, L Xia… - Cell death …, 2021 - nature.com
Nerves are important pathological elements of the microenvironment of tumors, including
those in pancreatic, colon and rectal, prostate, head and neck, and breast cancers. Recent …

Metal–organic frameworks for electrochemical sensors of neurotransmitters

LL Gao, EQ Gao - Coordination Chemistry Reviews, 2021 - Elsevier
Neurotransmitters (NTs) control many behavioral and physiological functions in central and
peripheral nervous system, and their detection is of great importance to disease diagnosis …

Non-small-cell lung cancer signaling pathways, metabolism, and PD-1/PD-L1 antibodies

M Santarpia, A Aguilar, I Chaib, AF Cardona, S Fancelli… - Cancers, 2020 - mdpi.com
Treatment of advanced (metastatic) non-small-cell lung cancer (NSCLC) is currently mainly
based on immunotherapy with antibodies against PD-1 or PD-L1, alone, or in combination …

Regulation of cisplatin resistance in lung cancer cells by nicotine, BDNF, and a β-adrenergic receptor blocker

R Ray, H Al Khashali, B Haddad, J Wareham… - International Journal of …, 2022 - mdpi.com
It is well-recognized that cigarette smoking is a primary risk factor in the development of non-
small cell lung cancer (NSCLC), known to account for~ 80% of all lung cancers with nicotine …