The rational design of anticancer platinum complexes: the importance of the structure-activity relationship
AM Montana, C Batalla - Current medicinal chemistry, 2009 - ingentaconnect.com
The ideal drug discovery process of new platinum based drugs should take into account
three basic fundaments: on one side the mechanisms of action and the corresponding target …
three basic fundaments: on one side the mechanisms of action and the corresponding target …
Low-lying electronic states of [Rh (bpy) 3] 3+,[Pt (bpy) 2] 2+, and [Ru (bpy) 3] 2+. A comparative study based on highly resolved and time-resolved spectra
H Yersin, W Humbs, J Strasser - Coordination chemistry reviews, 1997 - Elsevier
Optical emission and excitation spectra of [Rh (bpy-h8) 3] 3+,[Rh (bpy-h8) 2 (bpy-d8)] 3+,[Rh
(bpy-d8) 3] 3+,[Pt (bpy-h8) 2] 2+,[Pt (bpy-h8)(bpy-d8)] 2+,[Pt (bpy-d8) 2] 2+,[Ru (bpy-h8) 3] …
(bpy-d8) 3] 3+,[Pt (bpy-h8) 2] 2+,[Pt (bpy-h8)(bpy-d8)] 2+,[Pt (bpy-d8) 2] 2+,[Ru (bpy-h8) 3] …
Medicinal inorganic chemistry
Z Guo, PJ Sadler - Advances in inorganic chemistry, 1999 - Elsevier
Publisher Summary Biomedical inorganic chemistry “Elemental Medicine” is an important
new area of chemistry. Platinum complexes are now among the most widely used drugs for …
new area of chemistry. Platinum complexes are now among the most widely used drugs for …
Investigations of the reactivity, stability and biological activity of halido (NHC) gold (I) complexes
SK Goetzfried, P Kapitza, CM Gallati, A Nindl… - Dalton …, 2022 - pubs.rsc.org
The significance of the halido ligand (Cl−, Br−, I−) in halido [3-ethyl-4-phenyl-5-(2-
methoxypyridin-5-yl)-1-propyl-1, 3-dihydro-2H-imidazol-2-ylidene] gold (I) complexes (2–4) …
methoxypyridin-5-yl)-1-propyl-1, 3-dihydro-2H-imidazol-2-ylidene] gold (I) complexes (2–4) …
cis-[PtCl2(4,7-H-5-methyl-7-oxo[1,2,4]triazolo[1,5-a]pyrimidine)2]: A Sterically Restrictive New Cisplatin Analogue. Reaction Kinetics with Model Nucleobases …
JAR Navarro, JM Salas, MA Romero… - Journal of medicinal …, 1998 - ACS Publications
The formation and isolation of the antitumor drug cisplatin analogue cis-[PtCl2 (Hmtpo-N 3)
2]⊙ 2H2O (1)(where Hmtpo= 4, 7-H-5-methyl-7-oxo [1, 2, 4] triazolo [1, 5-a] pyrimidine) by …
2]⊙ 2H2O (1)(where Hmtpo= 4, 7-H-5-methyl-7-oxo [1, 2, 4] triazolo [1, 5-a] pyrimidine) by …
Comprehensive ab initio quantum mechanical and molecular orbital (MO) analysis of cisplatin: Structure, bonding, charge density, and vibrational frequencies
PNV Pavankumar, P Seetharamulu… - Journal of …, 1999 - Wiley Online Library
We carried out an extensive series of ab initio quantum mechanical (QM) calculations using
pure effective core potential (ECP) and hybrid Hartree–Fock (HF)/ECP basis sets, including …
pure effective core potential (ECP) and hybrid Hartree–Fock (HF)/ECP basis sets, including …
Stereochemistry of platinum coordination compounds
M Melnik, CE Holloway - Coordination chemistry reviews, 2006 - Elsevier
The coordination chemistry of platinum covers a huge field, as shown by a recent survey
covering the crystallographic and structural data of almost two thousand monomeric …
covering the crystallographic and structural data of almost two thousand monomeric …
The structures, cytotoxicity, apoptosis and molecular docking controlled by the aliphatic chain of palladium (II) complexes
MC Zhu, X Cui, S Zhang, L Liu, ZB Han… - Journal of Inorganic …, 2016 - Elsevier
A new series of Pd (II) complexes derived from benzenealkyl dicarboxylate ligands,[Pd (L
n)(phen)](phen= 2, 9-dimethyl-1, 10-phenanthroline, complex 1: L 1= phenylmalonate; …
n)(phen)](phen= 2, 9-dimethyl-1, 10-phenanthroline, complex 1: L 1= phenylmalonate; …
Synthesis, characterization and antiproliferative studies of the enantiomers of cis-[(1, 2-camphordiamine) dichloro] platinum (II) complexes
ÁM Montaña, FJ Bernal, J Lorenzo, C Farnós… - Bioorganic & medicinal …, 2008 - Elsevier
The platinum (II) complex cis-[(1S, 2R, 3S)-1, 7, 7-trimethylbicyclo [2.2. 1] heptane-2, 3-
diamine] dichloroplatinum (II)(1) and its enantiomer (2) have been synthesized and …
diamine] dichloroplatinum (II)(1) and its enantiomer (2) have been synthesized and …
New pH-dependent complexes, from mononuclear Pd (II) monomer to heteronuclear [Pd (II), K (I)] Polymer: DNA cleavage and cytotoxicity in vitro
EJ Gao, MC Zhu, Y Huang, L Liu, HY Liu, FC Liu… - European journal of …, 2010 - Elsevier
Two novel complexes, namely,[Pd (pdc) 2]·(dmp)· 6H2O (1) and [Pd (pdc) 2K (H2O) 5·
3H2O] n (2)[H2pdc= pyridine-2, 3-dicarboxylate acid, dmp= 2, 9-Dimethyl-1, 10 …
3H2O] n (2)[H2pdc= pyridine-2, 3-dicarboxylate acid, dmp= 2, 9-Dimethyl-1, 10 …